Comp Med 2015 (All issues) random questions

Question 1

genus species of gold fish

Answer 1

Carassius auratus

Question 2

genus species of the fish lice

Answer 2

Argulus japonicus

Question 3

Fish lice can be the vehicle for what other fish pathogens

Answer 3

Rhabdovirus carpio, Saprolegnia

Question 4

T or F

Mice have smaller erythrocytes with shorter lifespan than most other species

Answer 4

T

Question 5

T or F

Ringworm nuclear morphology is a normal feature of mice neutrophils, eosinophils and monocytes

Answer 5

T

Question 6

T or F

Mice have very high platelet counts compared to other mammals

Answer 6

T
900,000 to 1.6million/imcroliter
-5d lifespan, shorter than most species

Question 7

T or F

Bone marrow cellularity for mice is higher than most other species and does not decrease with age

Answer 7

T

Question 8

What is the primary site for iron storage in mice

Answer 8

Spleen

Question 9

T or F

The spleen remains an active site for hematopoeisis in mice throughout life

Answer 9

T

Question 10

What is the recommended maximal amount of blood that can be collected from mice, with a 4-wk recovery period?

Answer 10

15%

-average blood volume is 7.8ml/100g.

Question 11

What is the predominant leukocyte of most healthy wild type strains of mice?

Answer 11

lymphocytes

70-80% of the diff count

Question 12

T or F
Mouse neutrophils (and other granulocytes) may have the unique feature of ringworm or figure 8 nuclei?

Answer 12

T…picture of such in review article

Question 13

Is mouse norovirus an RNA or DNA virus?

Answer 13

RNA- ss

Caliciviridae

Question 14

What is the cellular tropism for infection by MNV

Answer 14

macrophages and dendritic cells

Question 15

T or F

MNV has been shown to increase macrophage content of atherosclerotic lesions in LDLr-/- mice fed an atherogenic diet

Answer 15

T

Question 16

What are myD88 mice deficient in?

Answer 16

Myeloid differentiation factor 88

used immunological research as models of IBD and diabetes

Question 17

What species of hamster has the most compressed reproductive cycle of any placental animals?

Answer 17

Phodopus sungorus

aka- siberian dwarf or djungarian hamster

Question 18

genus species of the big brown bat

Answer 18

Eptesicus cuscus

Question 19

What pathogen is thought to be the cause of white-nose syndrome in bats

Answer 19

Pseudogymnoascus destructans

Question 20

What tissue expresses corticotrophin releasing hormone in humans and anthropoid primates?

Answer 20

Placenta

Question 21

What are the common sources of gamma-irradiaters in use

Answer 21

137CS and 60Co
Regulated by the US Nuclear Regulatory Commission
require people with access to have background check and fingerprinting

Question 22

Name the novel species of Streptococcus was identified in weanling C57BL/6 mice presenting with running and neurologic signs

Answer 22

Streptococcus azizii

Question 23

What agent may be added to the drinking water of mice to induce IBD and dehydration?

Answer 23

DSS dextran sulfate sodium

Question 24

What is OCT (optical coherence tomography)

Answer 24

an imaging technique that used a thin wire and NEAR infrared to capture micrometer resolution from tissue

Question 25

What was Respiratory Inductance Plethsmoraphy used to measure in swine

Answer 25

Tidal volume | measures amplitude changes in ribcage and abdomen movements and correlates to tidal volume

Question 26

T or F | Squirrel monkeys are some of the most susceptible NHP species for experimental infection with CJD

Answer 26

T

Question 27

T or F | Squirrel monkeys have been used for vaccine development for HTLV

Answer 27

T

Question 28

What type of virus is SaVH1, for which squirrel monkeys are the natural host

Answer 28

alpha herpes virus Saimiriine herpesvirus 1 (aka herpesvirus tamarinus) 90% seroprevalence in squirrel monkeys

Question 29

How many cases of human infection with SaHV1 have been reported?

Answer 29

none, | not believed to be zoonotic

Question 30

How is SaVH2 classified?

Answer 30

gamma herpes virus Saimiriine herpesvirus 2 (aka herpesvirus saimiri or HVS) closely related to Kaposis sarcoma virus (human herpes virus 8)

Question 31

What is the cellular tropism of SaHv2

Answer 31

T cells | know to cause lymphomas and t-cell leukemia in other neotrop species (but not squirrels)

Question 32

What category herpesvirus is SaHV3

Answer 32

gamma lymphcryptovirus most similar to EBV in humans

Question 33

What category herpesvirus is SaHV4

Answer 33

betaherpes Saimiriine herpes virus 4 Squirrel monkey cytomegalovirus

Question 34

What is the pathology caused by Squirrel monkey polyomavirus (SMPyV)

Answer 34

not know to be pathogenic in the host species | route of transmission unknown

Question 35

To what viral genus dos Squirrel monkey retrovirus belong (SMRV)

Answer 35

betaretrovirus | type D retrovirus

Question 36

To what viral genus does Simian foamy virus belong?

Answer 36

Spumavirus retrovirus no known pathology in host or other species cytoxic in cell culture causing big vacuoles (hence the name foamy virus)

Question 37

What is the likely natural host for Marburg virus

Answer 37

Egyptian fruit bat (Rousettes aegyptiacus)

Question 38

omega 3 and omega 6 fatty acids are categorized as poly or mono unsaturated fatty acids

Answer 38

poly- PUFA

Question 39

T or F | High intake of omega 6 PUFA may promote inflammation resulting in chronic inflammatory disease

Answer 39

T | appropriate dietary intakes for PUFA have not been established for most species

Question 40

T or F | Warm water fish species (zebrafish) require both omega 3 and omega 6 PUFA

Answer 40

T | Cold water species have a higher requirement for omega 3

Question 41

ErbB2tg mouse was recently used and characterized as a model for what human disease?

Answer 41

Hypertrophic cardiomyopathy - cardiac ErbB2tg receptor tyrosine kinase over expression - similar gross and ECG abnormalities as humans with HCM- prolonged QT intervals, wide QRS completes, high P and R

Question 42

genus species of cotton rat

Answer 42

Sigmodon hispidus

Question 43

The cotton rat is the preferred model for what common human virus causing upper airway infection, especially in young children?

Answer 43

RSV- respiratory syncytial virus | paramyxovirus-neg sense RNA

Question 44

What is the etiology of hepatosis dietetica in swine

Answer 44

vitamin E-selenium deficiency in growing pigs

Question 45

What are the 2 most commonly used mouse models of atherosclerosis?

Answer 45

mice deficient in ApoE or LDLr ApoE-/- or LDL-/- -both have impaired lipoprotein production and metabolism -LDLr-/- must consume a high fat, hight cholesterol diet to become atherogenic, ApoE-/- will develop athero spontaneously

Question 46

Is mouse norovirus a DNA or RNA virus

Answer 46

RNA, non enveloped | calicivirus

Question 47

What is the cellular tropism for MNV

Answer 47

dendritic cells and macrophages (and b cells)

Question 48

What gland produces melatonin. Are levels higher or lower at night?

Answer 48

pineal | higher levels at night

Question 49

T or F | Night time shift work has been shown to increase the risk of prostate cancer in men.

Answer 49

T

Question 50

What are struvite crystals composed of?

Answer 50

magnesium ammonium phosphate | aka triple phosphate

Question 51

according to a recent article what strain of Rats are likely predisposed to development of urolithiasis

Answer 51

Long evans | outbred

Question 52

What is the etiologic agent of Epizootic Catarrhal enteritis in ferrets

Answer 52

ferret enteric Coronavirus

Question 53

What type of virus (RNA or DNA) is responsible for Ferret Systemic Coronavirus (FRSCV) associated disease

Answer 53

RNA

Question 54

What are the common clinical signs associated with Ferret Systemic Coronavirus?

Answer 54

anorexia, weight loss, diarrhea, abdominal mass | -pyogranulomatous to granulomatous inflammation of multiple organs

Question 55

T or F One of the histological lesions associated with Ferret Systemic Corona virus may be cholesterol clefts in close association with multinucleate giant cells

Answer 55

T

Question 56

What other common ferret viral disease is a necessary differential for Ferret Systemic Coronavirus, and how are they differentiated

Answer 56

Aleutian disease (parvovirus) - can be diagnosed by PCR - FRSCV- can be diagnosed by serology/immunohistochem with FIPV3-70antibody - Aleutian disease is likely to also show hypergammaglobulinemia

Question 57

List 3 modes of injection that are used to produce a model on intracerbral hemorrhage dogs

Answer 57

balloon inflation blood injection bacterial collagenase-preferred because it mimics hematoma expansion

Question 58

Name a bacterial growth agar that is selective for Yersenia

Answer 58

Cefsulodin-irgasan-novobiocin