Jaundice

Question 1

Bilirubin

Answer 1

> 40 umol/L

Question 2

Add bilirubin excretion pic

Answer 2

C

Question 3

Unconjugated hyperbilirubinaemia

Answer 3

Prehepatic causes
Haemolysis (sickle cell), haematoma

Hepatic causes
Gilbert’s syndrome

Question 4

Conjugated hyperbilirubinaemia

Intrahepatic

Answer 4

• Hepatocellular disease
  1. Hepatitis (a/b/c/e etc.), alcohol, drugs, autoimmune
  2. Cirrhosis
• cholestatic disease (bile ducts)
  1. Drugs, mets, cirrhosis, sepsis, autoimmune

Question 5

Conjugated hyperbilirubinaemia

Post hepatic

Answer 5

• biliary tract causes
  1. Gallstones, stricture, carcinoma, extrinsic pressure
• pancreatic causes
  2. Carcinoma, pancreatitis