Flashcards in Jaundice and Biliary Disorders CIS Deck (25):
-reduced activity of urine diphosphate glucuronyl transferase
-reduced hepatic reuptake of conjugated bilirubin
-reduced excretory fxn of hepatocytes
-darkly pigmented liver!!
pancreatic cancer- sx
Cholelithiasis -inc risk?
-rapid weight loss, indian, diabetes
Cholelithasis- dec risk?
-low carb diet, exercise, coffee
porcelain gallbladder- risk for?
(usually seen incidentally)
-bacterial infection with Clostridium perfringens
cholecystitis- stone where?
Choledocholithiasis- stones where?
common bile duct
-risk factor for asc cholangitis!!
Asc cholangitis- most common cause?
common bile duct stone (choledocholithiasis)
Asc cholangitis- next step?
emergent ERCP!! (endoscopic retrograde cholangiopancreatography)
gallbladder- Somatic dysfxn
-T5-7 on right
-accum of cholesterol
Jaundice- clinically seen when?
bilirubin > 3 mg/dL!!! (normal 0.2-1.2)
-M > F
-caucasian, hispanic > Af Am
Gallstones- risk factors
-rapid weightl oss
-high intake of carbs
(F- Family hx, fair, fat, female, fertile, forty)
-low carb diet
-high intake of Mg and polyunsaturated fats
-high fiber diet
Acute cholecystitis- US findings
-GB wall thickening, pericholecystic fluid, sonographic murphy sign
Acute cholecystitis- complications
-perforation, gangrene, abscess, peritonitis, emphysematous cholecystitis
(common bile duct stone)
-best seen ERCP or EUS
(complication of ERCP- iatrogenic pancreatitis)
-bile duct diameter > 6 mm!!
-manifestation of chronic cholecystitis
-intramural calcification of GB wall
-dx- abd radiography- incidental calcified lesion!!!
-inc risk of gallbladder carcinoma!!!
Asc cholangitis- sx
-Charcot's triad- jaundice, fever, RUQ pain
-Charcot's triad + hypotension and confusion
Primary Sclerosing Cholangitis- imaging
-ERCP/MRCP- "beads on a string"
-liver bx- "onion skinning"