Juvenile Arthritis Flashcards

(29 cards)

1
Q

what are a few non specific lab findings for juvenile arthritis?

A

elevated WBC
mild normocytic anemia
elevated ESR
elevated CRP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what does joint fluid analysis often show in juvenile arthritis?

A

inflammatory…so some WBCs but not too many

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what three abs are found in juvenile arthritis?

A

anticyclic citrullinated peptide
RF
anitnuclear antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is oligo juvenile arthritis?

A

when only less than 4 joints are involved

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

when does oligo juvenile arthritis onset?

A

ages 1-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

where does oligo juvenile arthritis usually affect?

A

lower extermities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what may co occur with oligo juvenile arthritis?

A

uveitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is Rf negative poly juvenile arthritis?

A

more than 5 joints affected and no Rheumatoid factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when does RF negative juvenile polyarthritis onset?

A

1-3 yrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is positive in RF positive juvenile polyarthritis?

A

RF and anti CCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

when does RF positive juvenile polyarthritis onset?

A

9-11 yrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

where do rheumatoid factor abs bind?

A

the Fc portion of the IgG antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is enthesitis related arthritis?

A

arthritis accompanied by inflammation of tendon insertion sites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is a common finding in enthesitis related arthritis?

A

SI joint tenderness and anterior uveitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is positive in enesthetis related arthritis?

A

HLA B27

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

who gets more juvenile arthritis?

17
Q

who gets more enthesitis related arthritis?

18
Q

when is onset of enthesitis related arthritis?

A

late childhood/adolescence

19
Q

what is finding of juvenile psoriatic arthritis?

A

arthritis, psoriasis, dactylitis, nail pitting, psoriasis in first degree relative

20
Q

what are the two findings you have to have in systemic juvenile arthritis?

A

fever longer than two weeks and arthritis for 6 weeks

21
Q

what are the four secondary findings in systemic juvenile arthritis?

A

evanescent rash, lymphadenopathy, enlargement of liver/spleen, serositis

22
Q

what are symptoms of systemic juvenile arthritis?

A

fatigue, malaise, weight loss, myalgias, myositis

23
Q

name the fever type associated with systemic juvenile arthritis

A

quotidian fever

24
Q

what is a quotidian fever?

A

high fever1/2 times a day and return to baseline

25
what is the evanescent rash?
discrete small salmon pink macular lesions in systemic juvenile arthritis
26
where does the evanescent rash appear in systemic juvenile arthritis?
trunk and proximal extremities
27
what is a blood related issue that can occur in systemic juvenile arthritis?
macrophage activation syndrome
28
name the two IL-1 inhibitors used in systemic juvenile arthritis?
anakinra and canakinumab
29
what is the IL-6 inhibitor used in systemic juvenile arthritis?
tocilizumab