Flashcards in Kapitel 10 Deck (27)
Having both hydrophobic and hydrophilic regions - as in a phospholipid or a detergent molecule.
Pigmented protein found in the plasma membrane of a salt-loving archaeon - Halobacterium salinarium (Halobacterium halobium). Pumps protons out of the cell in response to light.
The carbohydrate-rich zone on the eukaryotic cell surface attributable to glycoproteins - glycolipids - and proteoglycans of the plasma membrane.
An abundant lipid molecule with a characteristic four-ring steroid structure. An important component of the plasma membranes of animal cells. (Figure 10–4)
The cytoskeletal network in the cortical region of the cytosol just beneath the plasma membrane.
Small amphiphilic molecule - more soluble in water than lipids - that disrupts hydrophobic associations and destroys the lipid bilayer thereby solubilizing membrane proteins.
Any glycolipid having one or more sialic acid residues in its structure. Found in the plasma membrane of eukaryotic cells and especially abundant in nerve cells. (Figure 10–16)
Lipid molecule with a sugar residue or oligosaccharide attached. (Panel 2–5 - pp. 98–99)
Lipid linkage by which some membrane proteins are bound to the membrane. The protein is joined - via an oligosaccharide linker - to a phosphatidylinositol anchor during its travel through the endoplasmic reticulum. (Figure 12–52)
glycosylphosphatidylinositol anchor (GPI anchor)
Dissolving readily in water. Literally - “water-loving.”
Not dissolving readily in water. Literally - “water-fearing.”
Protein that binds tightly to a specific sugar. Abundant lectins from plant seeds are used as affinity reagents to purify glycoproteins or to detect them on the surface of cells.
Thin double sheet of phospholipid molecules that forms the core structure of all cell membranes. The two layers of lipid molecules are packed with their hydrophobic tails pointing inward and their hydrophilic heads outward - exposed to water. (Figure 10–1 and Panel 2–5 - pp. 98–99)
lipid bilayer (phospholipid bilayer)
Storage form in cells for excess lipids; comprised of a single monolayer of phospholipids and proteins that surrounds neutral lipids that can be retrieved from droplets as required by the cell.
Small region of a membrane enriched in sphingolipids and cholesterol. (Figure 10–13)
Artificial phospholipid bilayer vesicle formed from an aqueous suspension of phospholipid molecules. (Figure 10–9)
In cells: volume enclosed by an organelle membrane. In tissues: volume enclosed by a sheet of cells.
Amphiphilic proteins of diverse structure and function that associate with the lipid bilayer of cell membranes. (Figure 10–17)
Membrane proteins not extending into the hydrophobic interior of the lipid bilayer but bound to either face of the membrane by noncovalent interactions with other membrane proteins. (Figure 10–17)
Attach to specific membrane regions as needed and act to control local membrane curvature and thus confer on membranes their characteristic three-dimensional shapes.
Membrane protein in which the polypeptide chain crosses the lipid bilayer more than once. (Figure 10–17)
multipass transmembrane protein
Phospholipid derived from glycerol - abundant in biomembranes. (Figures 10–2 and 10–3)
The main category of lipids used to construct biomembranes. Generally composed of two fatty acids linked through glycerol (or sphingosine) phosphate to one of a variety of polar groups. (FIgure 10–3 - and Panel 2–5 - pp. 98–99)
The membrane that surrounds a living cell. (Figure 10–1)
Membrane protein in which the polypeptide chain crosses the lipid bilayer only once. (Figure 10–17 and 10-24)
single-pass transmembrane protein
Abundant protein associated with the cytosolic side of the plasma membrane in red blood cells - forming a network that supports the membrane. Also present in other cells. (Figure 10–38)