L17: Water Soluble Vitamins (BC) Flashcards Preview

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Flashcards in L17: Water Soluble Vitamins (BC) Deck (23)
1

*List the water soluble vitamins

  • B complexes
    -Thiamin (B1)
    -Riboflavin (B2)
    -Niacin
    -Cyanocobalamin (B12)
    -B6
    -Biotin
    -Folic acid (folate, folacin)
    -Pantothenic acid
    -Choline
  • Vitamin C

2

*What is the function of VB1 (Thiamin)?

  • CHO metabolism
    -oxidative decarboxylation of pyruvate to acetyl CoA (TCA cycle)
    -Pentose phosphate pathway
    Synthesis of branched chain AA
  • Nerve transmission (thiamin triphosphate)

3

*List some good dietary sources of VB1 (Thiamin)?

  • Green leaves
  • cereal grains
  • yeasts
  • microbial synthesis usually enough

4

*Describe the deficiency symptoms of VB1 (Thiamin)?

  • anorexia
  • inappetite
  • incoordination
  • muscle weakness (pyruvate accumulates)
  • Bracken fern poisoning (contains thiaminase which destroys thiamin)

5

*What is the function of VB2 (Riboflavin)?

  • Part of flavoproteins involved in H transport
  • FAD (flavin adenine nucleotide)
  • FMN (flavin mononucleotide)

6

*List some good dietary sources of VB2 (Riboflavin)?

  • high in fresh forage and yeast (5-20mg/kg)
  • low in cereals
  • microbes usually synthesise enough

7

*Describe the deficiency symptoms of VB2 (Riboflavin)

  • rough hair coat
  • vomiting
  • poor feed utilisation
  • curled toe paralysis (chics)
  • ophthalmia (eye inflamm)

8

*What is the function of Niacin?

  • Required for NAD and NADP+
    -energy metabolism (H transfer)
  • produced by microbes and in body from tryptophan

9

*List dietary sources of Niacin

  • Yeast
  • sunflower meal
  • low in cereals as bound

10

*Describe the deficiency symptoms of Niacin

  • poor growth
  • anorexia
  • dermatitis and pellagra
  • bone and feather abnormalities

11

*What is the function of VB12 (cyanocobalamin)?

  • needed for several enzyme systems
    -isomerases
    -dehydrases
    -methionine
    -DNA and RBC synth
    -proprionate conversion to succinic acid
  • Synthesised by microbes though Cobalt required

12

*Describe the deficiency symptoms of VB12 (cyanocobalamin)

  • growth retardation
  • poor feathering
  • often used in performance horses to prevent anaemia and enhance performance
    (no evidence, but helps w/ inappetance)

13

*What is the function of VB6?

Where is it found?

  • needed for:
    -aa metabolism
    -glycogen and lipid metabolism
    -adrenalin and noradrenalin synth
  • widely distributed in plants

14

*Dscribe the deficiency symptoms of VB6

  • def rare
  • poor growth
  • convulsions
  • anaemia

15

*What is the function of Biotin?

  • Coenzyme in carboxylation
    -needed for CHO and nucleic acid metabolism

16

*What are the deficiency symptoms of biotin?

  • PIGS
    -foot lesions
    -alopecia
    -dry scaly skin
    -poor growth rate
  • POULTRY
    -poor growth
    -dermatitis
    -cracked feet
    -poor feathering
    -fatty liver and kidney issues
  • Horses
    -crumbly hoof

17

*What is the function of Folic acid?

  • Part of coenzyme that adds/removes single C units into molecules
  • Essential for synthesis of:
    -Histidine
    -Serine
    -Glycine
    -Methionine
    -Purines
    -RNA
    -DNA

18

*List sources of Folic acid

  • fresh forage
  • cereals
  • oilseed meals
  • destroyed by UV light, heat, moisture
  • stored in liver

19

*Describe deficiency symptoms of Folic acid

  • low growth rate
  • anaemia
  • poor bone development

20

*What is the function of Pantothenic acid?

  • Part of CoA
    -FA oxidation
    -acetic acid metabolism
    -cholesterol and steroid synth
    -CHO and protein metabolism

21

*List sources and deficiency symptoms of Pantothenic acid

  • Widely distributed
  • rough hair coat/loss
  • slow growth
  • goose stepping

22

*What is the function of VC (ascorbic acid)?

  • antioxidant
  • enzyme in ETC reactions
  • collagen and noradrenalin synth
  • synthesised in liver from glucose (not in primates)

23

*Describe deficiency symptoms of VC (ascorbic acid)

  • SCURVY (DOG)
    -gingivitis
    -emaciation
    -diarrhoea
    -bone, teeth and cartilage defects
    -reduced infection resistance