L6-Lipids Flashcards

(73 cards)

0
Q

Lipids store energy as ______ to provide energy for making ___

A

hydrocarbons; ATP

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1
Q

The primary structural component of membranes are:

A

Phospholipid fatty acids

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2
Q

Lipids are messengers in the bloodstream as ______ and ______

A

hormones and prostaglandins

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3
Q

Lipids are which vitamins?

A

A D E and K-series

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4
Q

Dietary lipids are used to absorb vitamins from food; a human should have ___% of the diet in lipids to absorb enough vitamins

A

20

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5
Q

(T/F) Lipids are fats and are strongly hydrophobic

A

TRUE

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6
Q

3 Types of structural lipids are:

A
  1. Fatty acids
  2. Glycerols
  3. Sterols
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7
Q

4 types of lipids found in biological systems:

A
  1. Fatty acids
  2. Non-glyceride lipids
  3. Glycerides
  4. Complex Lipids
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8
Q

Glycerides such as diglycerides, triglycerides, and esp. _______ are made from _____ and ______

A

phospholipids; glycerol; fatty acids

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9
Q

Examples of complex lipids are

A

liposomes, micelles, lipoproteins and chylomicrons

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10
Q

3 different, unrelated types of non-glyceride lipids are

A

sterols, waxes and sphingolipids

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11
Q

The most crucial role of fatty acids in cells and tissues are as _____ chains in the structuring of ____ ____ ____, mostly as ______

A

aliphatic; cell bilayer membranes; phospholipids

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12
Q

Fatty acids also form messenger molecules like _____, and are transformed into energy storage molecules like ______ fats or ______ oils

A

prostaglandins; triglyceride; vegetable

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13
Q

Fatty acids can be used to emulsify non-polar and polar substances although they are non-polar because

A

they have acid heads then lend some solubility in water

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14
Q

_____ are salts of fatty acids

A

soaps

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15
Q

A fatty acid is a _____ chain with single or double chain, capped with a ______ group on one end and _____ on the other

A

hydrocarbon; methyl; carboxyl

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16
Q

A fatty acid has a ____ group that is easily replaced or added to so it can combine with other molecules

A

carboxyl

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17
Q

What creates a phospholipid?

A

Phosphate bonded to fatty acid

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18
Q

______ is a major component of bilayer membranes and is also a ______, an emusifier

A

Phosphatidycholine; diglyceride

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19
Q

What can emulsifiers do?

A

Able to get non-polar and polar substances to go into solution in water

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20
Q

Hydrophilic Phosphate/ Amine ______;

Hydrophobic Fatty Acid ______

A

Heads; Tails

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21
Q

Cholesterol is based on ______ (a non-glyceride lipid)

A

Sterol

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22
Q

The sterol backbone is composed of:

A

three 6-carbon rings

one 5-carbon ring

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23
Q

What is the precursor molecule for sterol-based compounds?

A

Cholesterol

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24
Sphingolipid is a non-_______ lipid
glyceride
25
Sphingolipids are constructed from a fatty acid called ______ that contain:
``` Sphingosine amino (nitrogen-containing) alcohol and a long chain fatty acid ```
26
What are sphingolipids important for?
Maintaining and improve function of the plasmalemma and occur in many forms
27
Glyceride molecules are built from a ______ molecule, and have _ known types which are:
glycerol; 3; mono-, di-, and triglycerides
28
How are glycerides named?
By the number of fatty acid chains attached to the glycerol backbone
29
Two important _______ are used in the lipid bilayer, and compose the phosphoglycerides which are _____ and _____
diglycerides; phosphatidycholine and phosphatidylethanolamine
30
______ are the most common way animals store fat in adipose tissue
Triglycerides
31
Triglycerides can be broken down and converted to energy as needed, and have a high caloric value, almost double of ________
carbohydrates
32
Triglyceride molecules packed in cells create:
fat tissue
33
A small sphere of bilayer and stores or transports polar, water soluble molecules
Liposome
34
A single later of phospholipid and stores or transports non-polar, fat soluble molecules
Micelle
35
A chylomicron is a type of lipoprotein ______ that transports triglycerides and cholesterol throughout the body in the bloodstream
micelle
36
What are the two most common lipid messengers?
Prostaglandins and sterols
37
(T/F) Hormones can be made from nucleotides, peptides, and amino acids
true
38
Prostaglandins are made from _____ _____
arachidonic acid
39
Arachidonic acid is made from _____ _____, an essential fatty acid that humans must get from _____
linoeic acid; diet
40
Arachidonic acid is converted into many types of ________ which are important for many messenger roles: in blood clotting, creating an inflammatory response, in menstrual cramping, protecting stomach lining, and bronchorestriction and bronchodilation in LU
prostaglandin
41
Sterol backbone molecules are utilized to produce _____, digestive ____ _____, and cholesterol
hormones, bile acids, cholesterol
42
Important gonadal (sex glands) hormones are steroid: (4)
testosterone, estriol, estradiol, progesterone
43
Adrenal hormones _____ and ______ regulate many crucial and important processes in the body's immune response, usually by turning off inflammatory processes.
glucocorticoids; corticosteroids
44
______ is a prime example of a synthetic and medical use of sterol hormones used to help with inflammatory diseases because of the side effects
Prednisone
45
Lipid messengers (sterol or prostaglandin) enter a site on a plasmalemma enzyme, called a ___ _____ and begin a chain of events to signal the cell of changed conditions
cell receptor
46
Carbohydrates are digested by enzymes in the ____ and _____ ____ into monomers that are easily absorbed through the ____ _____ directly into the bloodstream
saliva; small intestine; small intestine
47
Lipids pass through the stomach into the _____ and _____ where bile salts delivered from the ______ break up lipid globules into small ____
duodenum; jejunum; liver; micelles
48
The micelles are small enough to fuse with small intestine epithelial cells by ______, and begin their digestive journey
endocytosis
49
SI is carpeted with micrometer ____ that expose a lot of SA to the lumen so they can absorb digestate
villi
50
When a lipid globule enters the duodenum, sensory nerves tell the LV to excrete ______
bile
51
(T/F) GB only activated when large quantities of fat are sensed
TRUE
52
Bile and ______, also known as _______ break the globule and surround the fat, making micelles, or _____
lecithins (emulsifiers); droplets
53
______ enzymes excreted from the _____ into the duodenum enter the micelles and begin breaking down the complex fats (usually ____ and ______)
Lipase; pancreas; triglycerides and cholesterol
54
The micelles are absorbed through ______ by the _____ cells that line the SI lumen; Micelles are passed to the _____ cells for processing
Endocytosis; endothelial; parenchyma
55
In the parenchyma cells, the micelles are _________ and become _______, then released from golgi system, and are transported by _______ to the lymph lacteal in the center of the villus
proteinated; chlyomicrons; lacteals; exocytosis
56
A tube of cells that are the smallest in the lymph system:
Lymph lacteal
57
The chylomicrons travel in the lymphs until they are released into the :
bloodstream
58
When chylomicrons are released into bloodstream, the lipases in the chylomicrons begin ______ of fats and the resulting _____ and ___ _____ in the chylomicrons can be taken up by cells for their needs
Catalysis; glycerols; fatty acids
59
Excess glycerols and fatty acids are taken up by adipose tissue and converted into ____ ____ and stored
triglyeride fats
60
Lymphatic system empties into the bloodstream at the:
Superior vena cava near heart
61
B-oxidation is an important step in providing metabolites for the ____ ___ using lipids for fuel
Krebs Cycle
62
(T/F) It's harder to get rid of excess body fat (triglycerides)because B-oxidation is a very efficient way to burn calories to make ATP
TRUE
63
B-oxidation is a _______ / ________process because it degrades fatty acids into component parts in measured steps
degradation; catabolic
64
Where does B-oxidation take place?
Mitochondrion
65
For each acetyl group that enters B-Oxidation:
You use 2 coenzyme A and 1 ATP | Produce abundance of coenzyme A
66
1 FADH2 and 1NADH are produced for every __________ oxidized away from the fatty acid
2-carbon acetyl group
67
What is the most common way to metabolize lipids for energy generation?
B-Oxidation
68
B-Oxidation directly feeds the _____ _____ (step 2 of aeobic energy generation)
Krebs Cycle
69
B-oxidation produces ________ for every _______ degraded from a fatty acid chain
1 Acetyl Coenzyme A (ACA) | 2-carbon acetyl group
70
For every 2-Carbon acetyl group:
1 ATP consumed | 1 NADH and 1 FADh2 produced
71
Where does B-Oxidation take place
Matrix of mitrochondria
72
(T/F) B-Oxidation is super super efficient for generating ATP
True son.