L8: Schizophrenia & Other Psychotic Disorders Flashcards

1
Q

Def of Schizophrenia

A

A clinical syndrome of disruptive psychopathology characterized by:

  • Disturbance in: Thinking, Emotions and Behavior
  • Chronic course
  • 3 phases: Prodromal → Active → Residual
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Etiology of Schizophrenia

A
  • Biological
  • Psychosocial and Environmental factors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Epidemeology of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Biological factors related of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Psychosocial & Environmental factors of Schizophrenia

A

High expressed emotion families (High E E): Over critical, overinvolved, hostile - high relapse rate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Clincal types of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Types of symptoms of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Clinical Picture aspects of Schizophrenia

A
  • Onset & Course
  • Talk
  • Disorder of Thought
  • Disorder of Perception
  • Disorder of affect
  • Motor symptoms Catatonic Symptoms
  • Cognitive symptoms
  • Hostility & Aggression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
  • Think of +ve symptoms as things that are …. onto normal behavior.
  • Think of -ve symptoms as things that are ……. or missing from normal behavior.
A
  • Added, Subtracted
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

DSM5Cr of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Onset & Course of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Disorders of thought in Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Talk in Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Disorders of Affect in Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Disorders of perception in Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Motor symptoms (Catatonic Symptoms) of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cognitive symptoms of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Suicide Risk in Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Hostility & Aggression in Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

DDx of Schizophrenia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Indications of hospitalization of schizophrenia

A
21
Q

Prognosis of Schizophrenia

A
  • From 10-20% have good outcome
  • Up to 50% have poor outcome, with repeated hospitalizations, exacerbations of symptoms, and suicide attempts.
  • 20% to 30% of patients continue to experience moderate symptoms.
22
Q

Good Prognosis indicators in Schizophrenia

A
23
Q

Managment of Schizophrenia

A
24
Q

Antipsychotics in TTT of Schizophrenia

A
25
Q

Select the right drug carefully in TTT of Schizophrenia, evaluating:

A
  1. Efficacy
  2. How it makes the patient feel (eg, sedated)
  3. How it affects patient health (eg, weight gain, metabolic risks)
  • Include evidence-based psychosocial treatment or rehabilitation
26
Q

Elderly, medically ill patients who present with psychotic symptoms such as hallucinations, confusion, or paranoia should be carefully evaluated for …….. , which is a far more common finding in this population.

A

Delirium

27
Q

Stereotyped movement, bizarre posturing, and muscle rigidity are examples of …….., a syndrome which can be seen in …………

A
  • catatonia
  • schizophrenia, depression, bipolar disorder, and other psychiatric conditions.
28
Q

Response of Positive & Negative Symptoms to antipsychotics

A
  • Positive symptoms tend to respond more robustly to antipsychotic medications
  • Negative symptoms are more often treatment resistant and contribute significantly to the social isolation and impaired function of schizophrenic patients
29
Q

what are other psychotic disorders?

A
  1. Brief psychotic disorders.
  2. Schizophreniform disorders.
  3. Schizoaffective disorders.
  4. Delusional disorders.
  5. Psychotic disorders not otherwise specified. (Postpartum psychosis)
  6. Psychotic disorders due to GMC & SAD.
30
Q

Characters of Brief Psychotic Disorder

A
31
Q

Epidemeology of Brief Psychotic Disorder

A
32
Q

Managment of Brief Psychotic Disorder

A
32
Q

DSM5Cr of Brief Psychotic Disorder

A
33
Q

Epidemeology of Schizophreniform Disorder

A

A. Lifetime prevalence of is approximately 0.2%.

B. Males : females are equal

C. Depressive symptoms commonly coexist and are associated with an increased suicide risk.

34
Q

DSM5Cr of Schizophreniform Disorder

A
35
Q

Managment of Schizophreniform Disorder

A
35
Q

DSM5Cr of Schizoaffective Disorder

A
35
Q

Clinical Features in Schizophreniform Disorder

A
  • Symptomatology, including positive and negative psychotic features, is the same as schizophrenia.
  • Social and occupational functioning may or may not be impaired.
36
Q

Types of Schizoaffective Disorder

A

Bipolar Type:
- Diagnosed when a manic or mixed episode occurs Major depression may also occur.

Depressive type:
- Diagnosed if only major depressive episodes occur.

37
Q

Epidemeology of **Schizoaffective D

A
  • The lifetime prevalence is < 1%
  • First-degree biological relatives of schizoaffective disorder patients have an increased risk of schizophrenia as well as mood disorders
38
Q

Managment of Schizoaffective Disorder

A
39
Q

DSM5Cr of Delusional Disorder

A
40
Q

Epidemeology of Delusional Disorder

A
  • The prevalence is about 0.03%.
  • Mean age of onset is between 35-45 years
  • Males and females are equal
41
Q

Clinical Features of Delusional Disorder

A
  1. The presence of a non-bizarre delusion is the cardinal feature of this disorder.
  2. The delusion must be plausible, such as believing that someone is trying to harm them.
  3. Patient’s thought processes are normal except when discussing the specific delusion.
  4. The insight of patients into their illness is generally poor.
42
Q

Types of Delusional Disorder

A
43
Q

Managment of Delusional Disorder

A

Antipsychotics:
1. Start low and go slow to gain the compliance of the patient
2. Give trial for 6 weeks the either augment or substitute.
3. Delusional disorders are often refractory to antipsychotic medication.
4. The previous response is the best guide to antipsychotic selection.

Psychotherapy:
- family or couples therapy, may offer some benefit

44
Q

Prognastic factors in Schizophrenia

A
45
Q

Time Course of schizophrenia spectrum disorders

A
46
Q

Prognosis of psychotic disorders from Best to Worst

A

Mood disorder with psychotic features > schizoaffective disorder > schizophreniform disorder > schizophrenia.

47
Q

Difference between schizophrenia & delusional disorder

A