Lab 1 Test

Question 1

Outer spikes composed of glycoproteins

( key to unlock the door)

For enveloped

Answer 1

Peplomers

Question 2

Posses stabilizing proteins for envelope

Answer 2

Enveloped viruses

Question 3

allows the virus to survive a lil longer outside of host tissue

Answer 3

Matrix or Tegaument proteins

Ex. Giving herpes from shared use of warm towel

Question 4

Make DNA from RNA template

Answer 4

Reverse Transcriptase

Question 5

Cuts viral multi proteins ( fast viruses )

Answer 5

Protease

Question 6

Connect viral genes to host genome ( incorporation) to make provirus

Answer 6

Integrase

Question 7

Allows viral DNa to become apart of a host cells genome forever

Answer 7

Integrase

Question 8

Proviruis

Question 9

Uses rna temples to contruct new complentary rna

Depends on rna to make new rna

Answer 9

RNA dependent rna transcriptase

Question 10

Digest peptoglican in cell wall

Bacteriophages only

Answer 10

Lysozyme

Question 11

How many enzymes

Answer 11

5

Question 12

Tail fibers responsible for attaching to the correct bacterial host cell

Answer 12

Viral construction of bacteriophages

Question 13

Where is the lysozyme located

Answer 13

On the base plate

Question 14

Virulent virus

Answer 14

Lyric cycle , replication

Question 15

Is the lyric cycle quick or slow

Answer 15

Quick ( immediate )

Question 16

What does the lyric cycle do

Answer 16

Take over and doesn’t allow cells to have its normal function

( destroy cells )

Question 17

Temperate virus
(Delayed)

Answer 17

Lysogenic cycle

Ex. AIDS ( takes time to develop symptoms))

Question 18

What are the parts of the lytic life cycle

Answer 18

1. Attachment
2. Entry
3. Bacterial chromosome degraded
4. Synthesis
5. Assembly
   6.release

Question 19

The virus particle sticks to the outside surface of the correct host cell

Virus binds to receptor proteins by ligand proteins

Answer 19

Attachment

Question 20

Genetic material gets inside the host cell

Answer 20

Entry

Question 21

Making all the baby viruses parts , all the parts you need to construct a new baby

Answer 21

Synthesis

Question 22

All the new virus parts are put together

Answer 22

Assembly

Question 23

Once all cells are put together the cell is going to explode or burst and will be released to a new host cell

Answer 23

Release

Question 24

Naked
Animal viral attachment
What’s the ligand

Answer 24

Capsomeres

Question 25

Enveloped Animal viral attachment What’s the ligand

Answer 25

Peplomers

Question 26

Genetic material enters through the cytoplasm What are the phages Step 2 of lytic cycle

Answer 26

Phages Lysozyme and contraction of tail

Question 27

Penetration in naked viruses

Answer 27

Endocytosis , followed by uncoating

Question 28

What is uncoating

Answer 28

Removal of the layers that are covering the genetic material

Question 29

Second way penetration in naked viruses is

Answer 29

Direct entry , like a poor it sits and the genome goes straight in

Question 30

Penetration in enveloped #1 is

Answer 30

Endocytosis

Question 31

Penetration in enveloped #2

Answer 31

Direct entry

Question 32

Penetration in enveloped virus #3

Answer 32

Fusion of envople and cell membrane, requires uncoating

Question 33

Produces viral parts 1. Genome copies 2. Proteins - Capsomeres -Peplomers and matrix if envopled - optional enzymes

Answer 33

Synthesis ( for every virus )

Question 34

Antiviral drugs attack

Answer 34

Synthesis

Question 35

In phages only , and goes to base plate of assembled capsid

Answer 35

Lysozymes

Question 36

During assembly what type of viruses only , Peplomers go to a membrane ( will become enveloped later )

Answer 36

Enveloped

Question 37

Assembly If multi proteins made protease cuts proteins apart , fold

Answer 37

Fast Viruses

Question 38

Phages for release

Answer 38

Host cells explode ( lysozyme released in cell. ) Naked 1. Host cells take on water to lose , or 3. Exocytosis

Question 39

Viruses must bud out of a membrane to gain

Answer 39

Envelope , Peplomers

Question 40

Capsomeres join in o form capsid

Answer 40

Assembly

Question 41

Cells release virus particles

Answer 41

Release

Question 42

Phages : Hosr cell explodes Lysozymes relased in cell

Answer 42

Release

Question 43

What are the stages of lysogenic life cycle

Answer 43

1. Attachment 2. Penetration 3. Incorporation ( viral genes joins host cell genome ) ( Integrase ) 4.synthesis ( only difference uses proviral dna in situ, no matter what genome type virus ) 5.assembly 6 release Antiviral drug Integrase inhibitors

Question 44

What are triggers activated from viral genes

Answer 44

Age Trauma Hormones Illness Uv radiation

Question 45

Which stage in the viral life cycle does drug nafamostat block

Answer 45

Attachment

Question 46

What causes cancer

Answer 46

When genetic changes disappear put normal controls on cell reproduction and behavior

Question 47

Apotheosis

Answer 47

Cell suicide

Question 48

Proto oncogene

Answer 48

Gene that has potential to cause cancer if misbehaves

Question 49

How many changes are needed to change status of genes

Answer 49

2 Gene it self and control gene

Answer 50

Can some inserted viruses activate proto oncogenes or act as oncogenes

Question 51

Proto oncogenes convert to oncogenes by mutation true or false

Answer 51

True

Question 52

Genital warts and cervical cancer

Answer 52

Human papilloma virus

Question 53

Hep b and c

Answer 53

Liver cancer

Question 54

Burkitts lymphoma

Answer 54

Human Herpes Virus 4

Question 55

Kaposis Sarcoma

Answer 55

Human Herpes Virus 8

Question 56

Prion disease

Answer 56

Mad cow disease Abnormal brains tureen to mush

Question 57

Normal occurring proteins

Answer 57

Alpha helix flexible

Question 58

Deformed versions of same proteins

Answer 58

Beta sheet flat

Question 59

Disease of sheep

Answer 59

Scrapie Scrap their bodies raw by rubbing against fences

Question 60

1st studied human prion disease Gradual loss of motor control and death Skin and muscle eaten by me. Brain eaten by women nd children

Answer 60

Kuru

Question 61

50-75 year old disease Hereditary , seen in England Linked to eating beef from BSE infected cows Human version of mad cow disease

Answer 61

Creutzfwldt jakob Disease