Lab 7 Flashcards

(38 cards)

1
Q

Generated by excitable cells, rapid reversal of polarity

A

Action potential

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2
Q

Rising phase of action potential

A

Depolarization

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3
Q

Falling phase of action potential

A

repolarization

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4
Q

Undershoot of AP

A

Hyperpolarization

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5
Q

Muscle cells of the heart, a phase of intermediate voltage precede the falling phase , extending duration of AP

A

Plateau phase

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6
Q

Action potential is an —–

A

All or none process

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7
Q

Specific information transmitted by the neurons encoded in the

A

Frequency of action potential and their velocity of conduction

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8
Q

When there is no electrical activity

Cell difference across the cell membrane

A

Resting potential

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9
Q

In resting potential is it negative inside or outside?

A

Negative inside

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10
Q

Potential difference or the transmembrane potential in neurons at rest

A

-70mv

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11
Q

These contributes to electrical activity of various cell bodies

A

Electrochemical pump, voltage gated channels Na, K leak channels , differential distribution of permeable and non permeable ions

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12
Q

AP, of a nerve can be visualized on a computer screen through

A

Chart or scope software

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13
Q

Which leg is dissected in frogs

A

Sciatic nerve

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14
Q

Where does the nerve placed?

A

Nerve chamber

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15
Q

Is a sciatic nerve compound or not

A

Compound nerve

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16
Q

Thick myelinated fibers have ____ thresholds and conduct impulse ____

A

Lower , faster

17
Q

Unmyelinated or smaller diameter fibers which need strong stimulus

A

High threshold and slow conduction

18
Q

2 peaks

A

Compound action potential

19
Q

How does resolution increase?

A

Increasing the distance between the stimulating and recording electrodes and using sub maximal stimuli

20
Q

What does the increasing of distance significant for

A

Nerves has more time to pull away and separate from the action potential of slower conducting nerves

21
Q

Strength increase =

A

Current begins to excite larger areas of the axon

22
Q

Result of using sub maximal stimuli

A

AP occurs more quickly and the latency of stimulation decreases

23
Q

Voltage at which neuron is sufficiently stimulated (depolarizer) to fire action potential

24
Q

At some stimulus voltage, all neurons reach threshold and fire all action potentials
Further increase will NOT recruit more axons to fire

A

Maximum response

25
Strength of stimulus is____ as the duration of stimulus
Reverse proportional
26
The minimal voltage over the longest duration of current flow milliseconds
Rheobase
27
Significance of rheobase
Progressive increase in pulse duration is no longer associated with a progressive decrease in voltage
28
The duration needed to produce a response at twice the rheobase strength
Chronoaxie
29
Indicative of excitability of differ t nerves dependent of Na channels
Chronoaxie
30
Significance of chronoaxie
If 2 nerves with the be same rheobase, chronoaxie the stimulus duration corresponding to twice the rheobase can give an indication of their relative excitabilities
31
Equation of conduction velocity
cv = d/t (cm/s)
32
Deflection caused by application of the voltage to the nerve
Stimulus artifact
33
Often studied by measuring difference between the sites of 2 electrodes
Biolectrical phenomena
34
Dropped on the nerve and increases the speed of conduction of AP
Warm ringers solution
35
Decrease conduction velocity
Cold fingers solution
36
Increasing the K+ ion concentration outside the axon will
Increase the rate at eh in potential will be generated or propagated
37
Reason of KCl increase AP
Higher k+ concentration outside will prevent k efflux making inside more positive and closer to depolarization in shorter time
38
Blocks voltage gated Na+ channels will inhibit propagation of AP
Lidocaine