What is this? What are the purple cells?
characterized by presence of neutrophils
What is this?
You can see presence of lymphocytes and plasma cells
What is this? What are the arrows indicating?
Top arrow: edema and inflammatory cells
Bottom arrow: vascular congestion secondary to increase blood flow initially, follwed by stasis
What is this? What type of exudate is this?
Acute pneumonia as shown by neutrophils within alveolar spaces
Example of purulen exudate
What is the arrow point to? How would you characterize this inflammation of the pleura
Acute inflammation of pleura with fibrin on the surface
What is the arrow pointing to?
An area of mucosal loss associated with acute inflammation and necrosis
What is this central area called? What type of inflammation? Hint -- a possible outcome of pneumonia
Pulmonary abscess formation
This is one possible outcome of acute inflammation
An abscess is a localize collection of pus associated with destruction of underlying normal tissue
What does this represent? And what are these cells?
black arrows: plasma cells with eccentric nucleus, adjacent pale area
green arrows: lymphocytes with single nucleus filling most of cell
What kind of cell is this?
What does this show? What is the big blob in the center?
Granuloma comprised of epithelioid histiocytes
Giant cells [langhans type] are in center
What is this? How can you tell?
Endematous tissue and new capillaries forming
What type of cell is this?
Expresses antigens of smooth muscle
responds to agents that contract smooth muscle
responsible for wound contraction
What is this? What are the arrows?
This is the early stage of a scar
The arrows in clockwise order starting top left:
- scale crust
- granulation tissue
What is this?
This is granulation tissue
the left arrow is new blood vessel formation
The right arrow is endematous stroma
What is this?
You can tell from the fibrosis and collagen depostion
What does the arrow point to?
Thin new epidermis forming above a scar
What is this?
thick collagen bundles in keloid scar
what is this
What type of cell does this point to?
What type of inflammatory cell does this show?
What type of cells are these?
A = lymphocyte - dark stained nucleus, little cytoplasm
B = neutrophil
Lymphocyte is smaller than neutrophil
What type of inflammatory cells here?
What type of cell? How do you know?
peri-nuclear halo = large golgi
What type of cells do arrows point to?
What is happening in this abnormal lung?
- alveolar spaces that normally contain air are filled with cellular infiltrate
What are the arrows pointing to in acute inflammation of the lung?
blood vessels dilated and backed with RBCs due to increased blood flow and vascular permeability
What are the pink strands the arrow is pointing to in this inflammatory response? What does it indicate?
presence of fibrin in extravascular space indicated increased vascular permeability [normally cannot get through vessel wall]
What kind of inflammatory cells are in this infection? Acute or chronic?
mostly lymphocytes and plasma cells
What kind of connective tissue in this infection? Why did it form?
Dense fibrous tissue
Fibrosis often accompanies chronic inflammation --> scar
What do the white circle and arrows point to?
white circle = granuloma
green arrow = epithelioid histiocytes [macrophages]
red arrow = multinucleated giant cell
yellow arrow = lymphocytes
What is this called? What type of necrosis? Likely cause?
Granuloma = Caseous necrosis
Arrows point to injured myocardial cells. Circles point to inflammatory cells. Describe the cellular changes? Type of cell death?
loss of nuclei [karyolysis]
Can you see any residual myocardial fibers? type of tissue? What do the arrows point to in this section of the myocardium?
- no myocardial fibers
loose fibrous connective tissue containing edema + blood
- thin walled blood vessels
Stain of myocardium following MI with immunoperoxidase stain CD31 to mark endothelial cells [in brown]. What are the structures? What type of tissue?
structures are capillaries being formed
this is granulation tissue
This appearance of the liver is a sign of what?