Lec 7 - Synaptic Integration Flashcards
ap remains constant throughout its duration so it is blank
electrotonic
trigger zone has the blank threshold
lowest
spatial summation changes the blank of the stimulus
intensity
epsp in motor neuron is caused by blank
glutamate
temporal summation changes the blank of the stimulus
frequency
increased frequency and temporal summation will result in calcium blank
facilitation
most inhibitory synapses are at dendritic shafts or the cell body nearest to the blank
trigger zone
presynaptic inhibition acts at blank synapses and decreases amount of blank release
axo axonic, nt
presynaptic inhibition functions to blank meaningless information
filter out (habituation)
mechanisms that accound for decreased quantal released and is PRESYNAPTIC
gabaB
these cells fine tunes muscle control by inhibiting weakly excited motor neurons and decreasing firing rate of strongly excited motor neurons
renshaw cell
blank receptors can modulate things
muscarinic
this is a neuropeptide released from unmyelinated pain fibers that causes burning pain sensation
substance p
this neuropeptide produces opioid like action that dulls pain perception
enkephalin
transmitter action is terminated by glial blank and axon terminal blank
uptake, reuptake
neuromodulators may modify these conductances via 2nd messengers
K+, Ca+
dopamine and norepinephrine are the only nt that only activate these receptors
muscarinic receptors
phosphoinositol system has the blank nt
Ach —muscarinic,gq, plc – ip3, dag, pkc, ca
cAMP system has the blank nt
dopamine— dopamine receptor, gs/gi, adenylyl cyclase— cAMP, PKA
2nd messenger yields significant blank of the extracellular signal
amplification
beta adrenergic makes blank
Gs
alpha adrenergic makes blank
Gi
phospholipase C yields blank second messengers
2
protein kinases blank signal transduction pathways
activate
