Lecture 02

Question 1

% water turnover in infant& adult

Answer 1

3% in adult, 10% in newborn infants

Question 2

% total body water & compartment in body mass

Answer 2

total body water(60% of body mass)
intracellular fluid(40% of body mass)
extracellular fluid(20% of body mass)
plasma(5% of body mass)
interstitial fluid(15% of body mass)
lymph(<1-2% of ECF)
transcellular fluid

Question 3

3 layer when blood is centrifuged

Answer 3

plasma, buffy layer(WBC& platelet), RBC

Question 4

Ht是什么的缩写，怎么计算，normal value

Answer 4

hematocrit
height of RBC coln/ height of whole blood coln
45%

Question 5

word for “the fluid which percolate btw individual cells”

Answer 5

interstitial fluid

Question 6

determine compartment volume

Answer 6

1)direct with desiccator干燥器
2)indicator dilution method

Question 7

requirement of indicator when measure total body water

Answer 7

cross cell membrane

Question 8

requirement of indicator when measure ECF

Answer 8

cross capillary wall

Question 9

word for “aggregate of small fluid volumes secreted by specific epithelial cells that line some body cavities”

Answer 9

transcellular fluid

Question 10

step when using indicator dilution method

Answer 10

introduce know quantity of indicator(radioactive/ color) into vein

allow time to equilibrate

remove know V of blood

centrifuge to obtain plasma

measure conc in unit V of plasma

V=Q/c

Question 11

requirement of indicator

Answer 11

non-toxic

diffuse readily

induce no changes in distribution of H2O btw compartment

easy to measure

Question 12

ion composition of ICF& ECF

Answer 12

ICF high in K, Mg, low in Na, Cl
ECF high in Na, Cl, low in K