LECTURE 10 - Extrachromosomal Inheritance Flashcards

(21 cards)

1
Q

Mendelian principles emphasized in eukaryotes, the genes controlling the phenotype is in the ______

however, there are important traits that can be controlled by genes in the _____

A

nucleus

cytoplasm

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2
Q

genes in the cytoplasm are _____ that act as agents for ______ _____

A
  • extranuclear
  • hereditary transmission
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3
Q

EXTRACHROMOSOMAL INHERITANCE

  • states that the transmission of these cytoplasmic elements are dependent on????
A
  • the transmission of cytoplasm from parents to daughter cells
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4
Q

does EXTRACHROMOSOMAL INHERITANCE follow mendelian laws?

A

No

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5
Q

MATERNAL INHERITANCE

  • a characteristic _____ in the results of a _____ ______ where the progenies show characteristics of their ___ parent

+ reason for this

  • implies transmission through the ______
A
  • difference
  • reciprocal cross
  • female
  • female gamete contributes the majority of the cytoplasm to the zygote
  • cytoplasm
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6
Q

NON-MAPPABILITY

  • the (inability/ability) of genes to show ______ (thus also affects the genes capability to be _____ )
A
  • linkages
  • mapped

*also shows extrachromosomal inheritance

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7
Q

NON-SEGREGATION

  • failure to show this under appropriate circumstance indicate ______ ______
A

extrachromosomal inheritance

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8
Q

NON-MENDELIAN SEGREGATION

  • states that when segregation occurs _____ with _____ segregation, ____-______ factors might have accounted for the phenotypic ______
A
  • inconsistently
  • chromosome
  • non-chromosomal
  • variation
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9
Q

INFECTION-LIKE TRANSMISSION

  • a ____ phenotype is transmitted (with/without) nuclear transmission; it seems _____ that ____ control the phenotype
A
  • heritable
  • without
  • unlikely
  • chromosomes
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10
Q

INDIFFERENCE TO NUCLEAR SUBSTITUTION

  • when heritable characteristics persist in the presence of nuclei known to have been associated with alternative characteristics, the ____ of ______ genetic material over the ____ may be ____ ____
A
  • control
  • nuclear
  • characteristic
  • ruled out
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11
Q

the inheritance of CHLOROPLASTS was first reported in ____ by _____ ____ in _____ ____ of ____ ____ plants

A

1909

Carl Correns

Mirabilis jalapa (underlined) of four o’clock plants

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12
Q

CYTOPLASMIC INHERITANCE OF CHLOROPLASTS

  • leaf color includes (3)?
  • follows ___ inheritance
A
  • green
  • white
  • variegated (patches of green and white)
  • maternal inheritance
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13
Q

nuclear / chromosomal genes

VS

cytoplasmic / extrachromosomal genes

A

N/C
- carried by chromosomes housed in nucleus

C/E
- carried by DNA housed in organelles (chloroplast & mitochondria) found in cytoplasm

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14
Q

CRITERIA FOR IDENTIFYING EC GENES

A
  1. difference in result of reciprocal crosses
  2. maternal inheritance
  3. non-mappability
    *do not show predictable linkage patterns
  4. non-segregation
    *expected gamete ratios are not shown in individuals
  5. non-mendelian segregation
    *doesnt follow the usual laws
  6. indifference to nuclear substitution
    *nuclear substitution does not affect phenotype of EC genes
  7. infection-like transmission
    *if an EC gene is infected to another cell, it would start and infection-like effect on new cell
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15
Q

which of the germ cells contribute to the ff:

  • cytoplasm of zygote
  • organelles of zygote
A

both are egg cells

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16
Q

the term used to describe the superiority of the F1 over its parents in terms of yield or other characteristics?

+ relevance in crop farming?

A

heterosis/hybrid vigor

since yung F1 gen have better phenotypic characteristics than parents, CROSS-POLLINATION must be done (and selfing is prevented) to produce better quality crops

17
Q

how can selfing in crops be prevented?

A

emasculation or detasseling

18
Q

in corn, CYTOPLASMIC MALE STERILITY is due to a gene in the ______ called the ____ gene

those with this gene will have ______ ______ ______ wherein ______ is NOT POSSIBLE

+ what type of gene can reverse this effect?

A
  • mitochondria
  • S gene
  • sterile male flowers
  • selfing

“restorer gene” so those that have RR or Rr gene are male fertile flowers

19
Q

GENETIC BASIS OF HETEROSIS (3)

A
  1. Dominance
    - accumulation of favourable dominant genes in the hybrid
  2. Overdominance

3, Epistasis
- non-allelic interaction

20
Q

refers to when mitochondrial DNA is inherited from only the mother

+ if both from father and mother?
+ this result is found in what study?
+ how many individuals showcase biparental mitochondrial transmission?
+ ^^ individuals showed what syndrome?

A

Homoplasmy

Heteroplasmy

  • Lou et al.
  • 17 individuals
  • Leigh Syndrome
21
Q

what mechanisms (2) are used to remove paternal mitochondria?

+ using what enzyme?

A
  1. lysosomal pathway
  2. autophagy

mitochondrial endonuclease G*

*nuclear genes involved in coding this are mutated in those with Leigh Syndrome