lecture 11 membrane transport Flashcards

1
Q

cell membranes are ________ permeable

A

selectively

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2
Q

review worksheet about what solutes than can cross a phospholipid bilayer

A

ok

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3
Q

what type of molcules pass directly between lipids forming the membrane

A

small hydrophobic and small uncharged polar molcules

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4
Q

small molecules that cannot use simple diffusion to cross a cell membrane use what

A

transporter proteins and facilitated diffusion

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5
Q

what is facilitated diffusion

A

diffusion with help (from the transporter protein

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6
Q

what is faciliatetd diffusion mediated by

A

channel prpteins and carrier proteins

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7
Q

what is channel protein mostly used by

A

ions

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8
Q

what are carrier proteins mostly used by

A

other small solutes

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9
Q

how do channel proteins work

A

make tunnel to pass through membrane

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10
Q

how do carrier proteins work

A

chnage coformation allow their solute to cross the membrane

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11
Q

most channel proteins are what

A

gated, which means they open and close in response to cellular conditions

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12
Q

examples gated channel protein

A

-binding of ligand
-change in electrical gradient
-mechanical trigger
-light activation

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13
Q

what do diffusion rates of ions through ion channels depend on

A

electrochemical gradients

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14
Q

typical electrochemical gradient of cellular conditions

A

membrane potential negative inside

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15
Q

active transport

A

movement of solutes against their concentration gradient

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16
Q

what does active transport require

A

energy, making system more organized

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17
Q

what is concentration gradient in terms of ions

A

electrochemical gradient

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18
Q

examples of active transport

A

coupled transport, ATP driven pump, light driven pump

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19
Q

coupled trasnport refers to

A

protein

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20
Q

what is coupled trasnport

A

two moleqs cross the membrane at some point in time but one moves positively and releases energy

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21
Q

what should you think when you hear pump

A

energy is required (active transport)

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22
Q

is Na+/K+ ATPase an example of coupled trasnport

23
Q

sodium potassium pump use what type of transport

24
Q

how does sodium potassium pump move

A

uses 1 ATP to move 3 Na+ out and 2 K+ in

25
what does sodium potassium pump hydrolyze
hydrolyzes ATP to make ADP
26
watch video on it
ok
27
what is the sodium potassium pump chiefly responsible for
maintaining the membrane potential of cells (the difference in charge on either side of a cell membrane)
28
importance of sodium potassium pump and the Na+ gradient
it drives the active transport of many other solutes across the membrane
29
what does Na+ influx with sodium-potassium pump begin
-an action potential in neurons (how a neuron relays a neural impulse) -begins muscle contraction by muscle cells
30
what do you need for influx with sodium-potassium pump
Na+ gradient
31
what is coupled transport also called
co-transport
32
what is coupled trasnport
the electrochemical gradient of one molecule drives the transport of another molecule against its concentration gradient
33
how many molecules cross the membrane with coupled transport
two
34
describe how the two molecules move with coupled transport
1)one cross by passive transport: releases energy (exergonic process) 2)crosses by active transport: requires energy (endergonic process)
35
what are two molecules that go into cell via coupled trasnport
glucose and Na+ -diffusion of Na+ (passive transport) provides energy to pump glucose against its concentration gradient 9active transport)
36
bulk trasnport
moves larger molecules (polymers) in and out of a cell and depend son membrane fusion and budding
37
what type of molecules are moved by passive and active transport
small molecukes
38
exocytosis
large molecules are secreted when a vesicle fuses with the plasma membrane
39
endocytosis
large molecules are taken in when the plasma membrane pinches inward, forming a vescile
40
what type of materials are transferred by exocytosis and endocytossi
larger materials acorss cell membrane
41
where do materials taken up by endocytosis usually end up
lysosome
42
what are proteins and polysaccharides made by ER and Golgi secreted by
the cell via exocytosis
43
what is budding and fusion of vesicles critical for
the synthesis and delivery of secreted and membrane proteins
44
what are three forms of endocytosis
-phagocytosis -pinocytosis -repceptor-meditated endocytosis
45
what is phagocytosis chiefly done by
white blood cells
46
phagocytosis
cell reaches out extensions that wrap around phagosomes (vacuoles)
47
do pinocytosis and recepto mediated endocytosis grab anything
no, but it reaches down invaginating and ingested materials get stuck in it.
48
with what form of endocytosis does cholesterol enter cell
receptor mediated endocytosis
49
summarize passive trasnport
high -> low [] movement -does not use [] -moves ions
50
summarize active tranport
-against [] gradient -uses energy -always requires protein
51
what do passive and active transport both involve
-movement of molecules across/through the membrane -proteins may be involved
52
what is [] gradident
diff in [] in 2 areas/2 regions separated by a membrane
53
are all solutes ions
no
54
what are ways active transport can obtain energy
-ATP driven pump -coupled transport -passive transport