Lecture 13: Cell signaling Flashcards

1
Q

What type of gas signaling molecule is in mammals?

A

nitric oxide

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2
Q

What type of gas signaling molecule is in plants?

A

ethylene

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3
Q

What type of signaling molecule is Adrenaline?

A

small polar

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4
Q

What type of signaling molecule is steroids?

A

small nonpolar

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5
Q

What type of signaling molecule is cytokines?

A

peptide

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6
Q

What type of signaling molecule are growth factors?

A

peptide

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7
Q

Define plasmodesmata

A

transport of molecules between cytoplasm and ER between cells

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8
Q

Where do plasmodesmata connect

A

between neighboring plant cells

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9
Q

Which organisms have gap junctions?

A

animals

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10
Q

which type of cell signaling involves rapid transmission of ions and small molecules across tissue?

A

gap junctions

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11
Q

What is gap junctions important for the heart?

A

muscle contraction

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12
Q

What happens in contact dependent signaling

A

neighbors receive instructions from neighbors

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13
Q

What two factors are in contact dependent signaling?

A

notch and delta
one turns on and one turns off

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14
Q

Define paracrine signaling

A

short distance signaling between cells

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15
Q

What period is paracrine signaling important in?

A

early development

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16
Q

Where is paracrine signaling happening in the body?

A

within organs

17
Q

Define endocrine signaling

A

signals travel by bloodstream

18
Q

Where is endocrine signaling happening in the body?

A

between multiple organs

19
Q

What type of signaling is estrogen and. testosterone in puberty

20
Q

What type of signaling are growth factors?

A

both paracrine and endocrine

21
Q

What type of signaling happens in bacteria when there’s many similar bacteria around?

A

quorum signaling

22
Q

What is quorum signaling dependent on?

A

high cell density

23
Q

What type of receptor is on the service of the cell?

A

extracellular

24
Q

What type of receptor is on the inside of the cell?

A

intracellular

25
what type of ligands do intracellular receptors receive
small, nonpolar
26
What type of receptor are activated by dimerization?
receptor kinase
27
What two types of receptors are activated by. conformational change
g coupled and ligand gated
28
What type of receptor signaling leads to long term responses?
receptor. kinase
29
What are PDGF?
platelet derived growth factor
30
What cells require PDGF to grow and survive?
mesenchymal cells
31
What are the 4 steps of cell signaling inside a recipient cell?
1. receptor activation 2. signal transduction 3. response 4. termination
32
What is a type of signaling that uses cascades of transductions?
RTK/MAPkinase signaling
33
Where does the hormone adrenaline bind
many organs
34
Where is adrenaline released from?
medulla of adrenal glands
35
What receptor does adrenaline bind to on organs?
beta-adrenergic receptors
36
What type of receptors are beta adrenergic receptors?
G-protein coupled
37
What type of receptors are the most diverse and abundant
G-protein coupled
38
What type of receptor are transmembrane proteins?
G-protein coupled
39
Where is the binding site located in a G-protein coupled?
topologically outside the cell