Lecture 14: Placental Physiology Flashcards Preview

Zak, Embryology > Lecture 14: Placental Physiology > Flashcards

Flashcards in Lecture 14: Placental Physiology Deck (19):
0

What are the 3 major functions of the placenta?

Diffusion of O2 and CO2, diffusion of foodstuffs, excretion of waste

1

What are characteristics of the early placenta?

Thick, low permeability, small surface area, diffusion conduction is miniscule

2

What are characteristics of the late placenta?

Thin, high permeability, large surface area, large placental diffusion

3

What is the PO2 of the mother late in pregnancy?

5o mmHg

4

What is the PO2 of the fetus late in pregnancy?

30 mmHg

5

What does the Bohr effect say?

Hemoglobin can carry more oxygen at a low PCO2

6

What sort of diffusion does foodstuffs use to cross the placenta?

Facilitated diffusion of glucose via trophoblast cells

7

What waste products diffuse from fetus to maternal blood?

Urea, uric acid, & creatinine

8

What does HCG secretion do?

1) Prevents involution and increases growth of corpus luteum
2) CL increase secretion of progesterone & estrogen
3) Interstitial cell-stimulating effect on testes
4) Production of testosterone until birth

9

Toward the end of pregnancy, _____ secretion levels are 30X higher than normal levels for the mother.

Estrogen

10

What does estrogen secretion do?

Causes enlargement of maternal parts: uterus, breasts, genitalia, etc.

11

Progesterone is secreted in _____ quantities by corpus luteum early and _____ quantities by the placenta

Small.
Large

12

What does progesterone secretion do?

1) Causes development of decidual cells
2) Decreases contractility of uterus
3) Increases fallopian tube and uterus secretions

13

What is HCS secreted by and when is it secreted?

Placenta beginning in 5th week

14

What does HCS secretion do?

1) Decreased insulin sensitivity & decreased use of glucose by mother
2) General metabolic hormone

15

What causes erythroblastosis fetalis?

Rh-positive fetuses being attacked by maternal anti-Rh antibodies

16

What is hydrops fetalis?

Billirubin from lysed RBC's causing water build up, jaundice, & brain damage

17

What is placenta previa?

Abnormal implantation of the placenta within the uterus

18

Chorionic villi characterized by nodular swellings is termed _____?

Hyatidiform mole