Lecture 19 Flashcards
stage 2 - CHO breakdown
2 pyruvate molecules degreade further to:
1- hydogen atoms (H)
2- ATP
stage 2 is called
citric acid cycle
purpose of stage 2
generate pairs of H atoms for trasnferr to the electron transport chain where majority of the ATP is produced
ATP produced 2 ways during CHO breakdown
- Directly in the glycolysis and CAC pathways
- Indirectly from pairs of H taken to the ETC by NAD and FAD
ETC
- pairs of H atoms are removed from all stages of CHO breakdown by NAD and FAD carriers
Points where H is sent to ETC in the CHO breakdown
- stage 2 where pyruvate is converted to acetyl CoA= 1 pair of H send to the ETC
- 4 points on the one CAC where H pairs are released
when are ATP produced during stage 1 and stage 2
- one ATP is produced in CAC after step 7. (2 CAC therefore 2 ATP are produced)
- stage 1 glycolysis = 2 ATP glucose
indirect production of ATP
- 90% of ATP is made indirectly in ETC
- H taken to the ETC by NAD + FAD will make ATP
what are the 2 rules of ATP
2 NAD will produce = 5 ATP
2 FAD will produce = 3 ATP
how many molecules are made
32 ATP if glucose
33 ATP if glycogen
fate of hydrogen in the ETC - ooxidative phosphorylation or aerobic metabolism
- H reaches the ETC and splits into proteins and electrons
- ETC is made up of cytochromes (electron carriers)
- pairs of electrons are passed down the cytochrome chain
- energy is relased which results in the phosphorylation of ADP and a Pi to ATP
- Finally, the electrons reach the end of the chain where they rejoin with H+ and oxygen (O2) to form water (H2O).
oxidative phosphorylation
Energy generated from electrons stripped from H in the ETC is used to phosphorylate ATP