Lecture 2 Flashcards
(46 cards)
Describe the difference in directional orientation systems found within the central nervous system.
Brain - top: dorsal - front - rostral - back - caudal - bottom - ventral Spinal Cord - top: rostral - front: ventral - back: dorsal - bottom: caudal
What are the 3 planes used to orient images in the central nervous system?
sagittal, coronal/frontal, horizontal/transverse
What structures make up the prosencephalon (and how are they further divided into the telencephalon and diencephalon)?
telencephalon - cerebral hemispheres, subcortical white matter, basal ganglia, basal forebrain nuclei
diencephalon - thalamus, hypothalamus, and epithalamus
What structures make up the mesencephalon?
cerebral peduncles, midbrain tectum, and midbrain tegmentum
What structures make up the rhombencephalon (and how are they further divided into the mesencephalon and myelencephalon)?
mesencephalon - pons and cerebellum
myelencephalon - medulla oblongata
Explain the difference between gray and white matter.
gray matter - neuron bodies, dendrites, axon terminals - majority of local synaptic communication
white matter - myelinated axons - majority of signal transmission
Define gyrus, sulcus and fissures with regards to central neuroanatomical structures.
- gyrus - ridges
- sulci - grooves
- fissures - big sulci
What is the function of the cranial vault and what bones comprise it?
- provide protection of brain and support facial structures
- total of 22 bones
- cranium (8) - frontal, 2 parietal, 2 temporal, 2 sphenoid, occipital
- facial bones (14)
What is regarded as a fossa in the cranial vault? What are the major fossae found in the human skull?
fossa - cavity/compartment
- anterior fossa - frontal lobe
- middle fossa - temporal lobe
- posterior fossa - cerebellum, brainstem
What function does a foramen hold in the skull?
openings in which cranial nerves, arteries, veins, and other structures pass
Identify the boundaries of the vertebral column. What runs through here?
- boundaries - vertebral body and vertebral arch (pedicles, laminas)
- spinal cord
Identify the boundaries of the intervertebral column. What runs through here?
- boundaries - vertebral body, intervertebral disc, facet joint, inferior notch of pedicle, and superior vertebral notch of pedicle below
- spinal nerve roots
What are the names of the meninges, and how are they oriented travelling superficially to deep?
dura mater, arachnoid mater, pia mater
What is the dura mater composed of? What is its role?
- periosteal layer (fused w/ skull) and meningeal layer (fused w/ periosteal layer)
- envelop and protect brain
- limit rotational displacement of brain
- Regulate generation and migration of neural progenitors
- Regulates proliferation and survival of radial glial cells
Describe the structural layout of the arachnoid mater. What is its role?
- web-like appearance with space in-between filled w/ CSF
- envelop and protect brain
- combats shearing of brain
- aids in CSF circulation
What is the role of the pia mater?
- Envelop and protect brain
- Aids in production of CSF
- Embeds superficial arteries and veins and serves as separation between neural tissue and blood vessels
↑ efficiency of blood brain barrier - Contributes to degradation of neurotransmitters
Define the spaces associated with the meninges. What is their function within the skull?
- epidural space and subdural space - too small to see unless pathology
- subarachnoid space - contains connective tissue trabeculae and intercommunicating channels w/ CSF; also houses superficial branches of cerebral arteries and veins
What is cerebrospinal fluid (CSF) composed of?
clear, colorless alkaline fluid w/ H2O, glucose, proteins, electrolytes, etc.
Where is CSF secreted, and what structures? Where is it reabsorbed?
- secreted by choroid plexus found in ventricles
- reabsorbed by arachnoid granulations
What are the functions of CSF?
- support and protect brain/spinal cord
- maintain pressure
- nutrition
- waste removal
What role does ventricles play in the CSF system? Where are they found?
- produce and distribute CSF
- lateral ventricle - cerebral hemisphere
- 3rd ventricle - thalamus and hypothalamus
- 4th ventricle - pons, medulla, and cerebellum
What is the route that CSF takes as it travels through the nervous system?
lateral ventricles - intraventricular foramen - 3rd ventricle - cerebral aqueduct of Sylvius - 4th ventricle - medial and lateral foramen - subarachnoid space of spinal cord/brain - arachnoid granulations
What is the role of the blood brain barrier?
barrier between bloodstream and extracellular space of brain
What types of material does the blood brain barrier allow in? What does it block?
- allows in: water, O2, small lipid-soluble substances
- blocks: toxins, pathogens, other potentially dangerous substances
- allows nicotine, alcohol, anesthesia across