Lecture 2

Question 1

nucleocapsid (naked capsid virus) structure

Answer 1

DNA or RNA
structural proteins
may have enzymes and nucleic acids or binding proteins

Question 2

enveloped virus structure

Answer 2

nucleocapsid
glycoproteins
membrane

Question 3

LD

Answer 3

lethal dose

Question 4

ID

Answer 4

infectious dose

Question 5

PD

Answer 5

paralytic dose (if agent paralyzes)

Question 6

LD50

Answer 6

dose that would kill 50% of population

Question 7

HeLa cell

Answer 7

tumor cells used in studies
from a woman, Henrietta Lacks
immortals cells

Question 8

titer

Answer 8

greatest dilution or smallest concentration of original viral sample that gives positive results

Question 9

satellite viruses

Answer 9

need helper virus to replicate

Question 10

pseudovirions

Answer 10

cellular DNA

Question 11

peplomers

Answer 11

proteins in envelope

Question 12

matrix protein

Answer 12

M or MA

between capsid and envelope

Question 13

capsid of an enveloped virus

Answer 13

can be spherical helical or bilateral

Question 14

capsomer

Answer 14

building blocks of the plasmid

Question 15

icosahedron

Answer 15

quasi-spherical shape of capsid
20 triangular faces
12 vertices