Lecture 2 Block 2 Flashcards
(31 cards)
what is the homeostatic condition for blood calcium in humans
8.5-11mg calcium/ 100mL blood
what is the homeostatic condition for blood pH in humans
7.4
what is the homeostatic condition for blood glucose in humans
90mg glucose/100mL blood
what is the homeostatic condition for body temp in humans
37 degrees celsius
what are the components in a homeostatic control system
a sensor, a control center, and effectros
what are the 2 types of feedback circuits
negative and positive
what are negative feedback loops
mechanism that works to counteract further changes of the parameter, reversal of detected change
what are positive feedback loops
mechanism that works to amplify changes of the parameter, change triggers amplification
what do receptors do
sense change in internal or external environment
what do control centers do
process information gathered from receptors and sends a response to effectors
what do effectors do
adjusts the regulated parameter
what is responsible for regulation of blood calcium
thyroid and parathyroid
what are the physiological roles of calcium
bone formation, muscle contraction, membrane excitability, blood clotting, intracellular activity
how do the kidneys and intestines control calcium levels
affect whether calcium taken in is either released through urine or defecation or reabsorbed
what is the job of the kidneys in regards to calcium
excretion or reabsorption
what is the job of the intestines in regards to calcium
storage
what is the job of the bones in regards to calcium
released or storage of calcium
what do parafollicular cells release when blood calcium is high
calcitonin
what does calcitonin do
causes inhibition of osteoclasts and decreased renal reabsorption of Ca2+
what does parathyroid gland release when blood calcium is low
parathyroid hormone
what does PTH do
increased osteoclast activity, increased intestinal reabsorption of calcium, and increased renal reabsorption of calcium
what is the pancreas responsible for
regulation of blood glucose
what is the Bohr shift
the effect of increased CO2 on oxygen dissociation curves for hemoglobin
what systems are responsible for maintaining blood pH
respiratory and renal systems