Lecture 2: Connective Tissue Flashcards

1
Q

major characteristic of CT

A

abundant matrix

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2
Q

most common cells found in CT

A

fibrocytes and fibroblasts

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3
Q

CT matrix is composed of?

A

cells
protein fibers
ground substance

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4
Q

most abundant protein fibers in CT

A

collagen

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5
Q

ground substance is composed of?

A

glycosaminoglycans

glycoproteins

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6
Q

most abundant type of collagen

A

type I

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7
Q

Type I collagen synthesis

A
pre-sequence 
propeptide secreted to extra matrix
peptidase cleavage of ends
now called tropocollagen
assembled polymer = collagen
64nm banding
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8
Q

CT functions

A
support and bind tissues
structural framework
oppose gravity
create body contours
house special cells
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9
Q

3 major classes of CT

A

embryonic
adult
special

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10
Q

embryonic CT

A

Wharton’s jelly found in the umbilical cord and pulp of developing teeth

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11
Q

adult CT

A

loose
dense
elastic
reticular

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12
Q

special CT

A

cartilage
bone
adipose
hematopoietic

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13
Q

types of protein fibers

A

collagen
elastic
reticular

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14
Q

define amorphous

A

non-cellular material

non-fibrous

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15
Q

amorphous ground substances

A

GAGs

glycoproteins

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16
Q

loose CT

A

or areolar
high cell>fiber content
beneath most organs
tunica adventitia

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17
Q

dense CT

A

white fibrous CT
high fiber>cell ratio
nonvascular
tendons/ligaments

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18
Q

reticular CT

A

branched network of reticular fibers

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19
Q

elastic CT

A

elastic fibers, appear like wavy lines

20
Q

2 types of adipose tissue

A

white and brown fat

21
Q

fat distributed throughout the body

A

white fate

22
Q

fat only found in newborns or hibernating animals

23
Q

what gives brown fat it’s color vs white fat?

A

abundant mitochondria

multiple lipid droplets unlike white fat

24
Q

all GAGs are covalently linked to _____ .

25
proteoglycans =
GAG + protein
26
list the 4 GAGs
hyaluronic acid heparin chondroitin sulfate keratin sulfate
27
Chondronectin
type of glycoprotein | adheres chondrocytes and collagen
28
laminin
type of glycoprotein | attaches epithelial cells to lamina propria
29
extracellular matrix of cartilage
collagen chondroitin sulfate proteoglycans
30
most common type of collagen in cartilage
type II | type I in fibrocartilage
31
outer fibrous layer surrounding a mass of cartilage and contains fibroblasts
perichondrium
32
types of cartilage
hyaline elastic fibrocartilage
33
cartilage that lacks a perichondrium
fibrocartilage | hyaline cartilage on top of epiphyses
34
are bones vascularized?
highly vascularized
35
components of bone matrix
osteoid | hydroxyapatite
36
major types of bone tissue
woven compact spongy
37
other names for compact bone
lamellar bone
38
other names for spongy bone
trabecular or cancellous bone
39
periosteum
outer fibrous layer of bone
40
lacuna
star shaped sites of active osteoblasts
41
lamella
space between canals of compact bone
42
canaliculus
tiny canals in compact bone that lead to the haversian canal
43
haversian canal
blood vessels within compact bone
44
Volkmann canal
provide canal for blood to flow in and out of haversian canals
45
why does bone appear like groups of circles?
because new tissue is layered on top of the old
46
one circle section of bone tissue
haversian system or osteon