Lecture 2: Connective Tissue Flashcards
major characteristic of CT
abundant matrix
most common cells found in CT
fibrocytes and fibroblasts
CT matrix is composed of?
cells
protein fibers
ground substance
most abundant protein fibers in CT
collagen
ground substance is composed of?
glycosaminoglycans
glycoproteins
most abundant type of collagen
type I
Type I collagen synthesis
pre-sequence propeptide secreted to extra matrix peptidase cleavage of ends now called tropocollagen assembled polymer = collagen 64nm banding
CT functions
support and bind tissues structural framework oppose gravity create body contours house special cells
3 major classes of CT
embryonic
adult
special
embryonic CT
Wharton’s jelly found in the umbilical cord and pulp of developing teeth
adult CT
loose
dense
elastic
reticular
special CT
cartilage
bone
adipose
hematopoietic
types of protein fibers
collagen
elastic
reticular
define amorphous
non-cellular material
non-fibrous
amorphous ground substances
GAGs
glycoproteins
loose CT
or areolar
high cell>fiber content
beneath most organs
tunica adventitia
dense CT
white fibrous CT
high fiber>cell ratio
nonvascular
tendons/ligaments
reticular CT
branched network of reticular fibers
elastic CT
elastic fibers, appear like wavy lines
2 types of adipose tissue
white and brown fat
fat distributed throughout the body
white fate
fat only found in newborns or hibernating animals
brown fat
what gives brown fat it’s color vs white fat?
abundant mitochondria
multiple lipid droplets unlike white fat
all GAGs are covalently linked to _____ .
protein