lecture 20 Flashcards

1
Q

commensals/ mutualistic

A

microbes that are not causing harm but rather benefitting u

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2
Q

Gastrointestinal microbata is made up of

A

large bacteriodetes
Firmicutes
Proteobacteria

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3
Q

Function of gastrointestinal microbata

A

they are unique and train immune system on how to respond

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4
Q

gastrointestinal microbata has a

A

gut “enterotype”

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5
Q

gastrointestinal iof the stimach

A

helicobacteri pylori
gastric lumner ph1-2
mucuc layer at wall pH 6-7

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6
Q

which diseases is found in 50 % of world population, causes irritation of the stomach

A

Helicobacter pylori

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7
Q

gastrointestinal iof the small intestine ph

A

the further away from the duodemum, the decrease in pH

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8
Q

as small intestine becomes more acid, what happens to microbes

A

less microbes is found.

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9
Q

what species do you expect to find in small intestine

A

enterococci and lactobacilli

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10
Q

amount of species in large intestine

A

10^10- 10^11 bacteria/gram

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11
Q

what kind of species foundin large intetsine

A

mostly anaerobes like faculatative (E.coli), Archaea-methanogens, yeast-candidia

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12
Q

remember amino acid, organix acis, vitamins product or enzymes

A

thiamine, riboflavin, pyridocine, B12

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13
Q

skin microbiota is made up of what species

A

bacteria anf yeasts

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14
Q

number of species in skin microbiota

A

10^6 bacteria/cm^2

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15
Q

s influenced by

A

sweat
wether
health
age
pets
personal hygiene

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16
Q

function of skin and mucous membrane

A

barrier to infection

17
Q

what is competeitve exclusion

A

is when the skin rstricts the outside and insude

18
Q

skin is on

A

the outside

19
Q

mucous membrane is on

A

the inside

20
Q

when is the first time you are colonized

A

immediately after birth by mother

21
Q

vaginal vs C section microbiome changes

A

children share 72% of mother biome compared to 42% of C section

22
Q

breast milk vs formula milk microbiome chnage

A

more lactobacillus, bifidobacterium in breast milk.

23
Q

function of B’longum

A

digest complex breast milk polysaccharides

24
Q

as the diversity of microbiome decrease, what happens to species

A

more bacteriodetes, less firmicutes more diseases

25
what is dysbiosis
disruption of the homeostasis between microbiota and the host
26
characteristics of inflammatory bowel disease
chronic gut inflammation altered gut microbiota
27
comparing IBD patient with healthy subsject, which has more diveristy
reduced functional diversity in IBD patients
28
what is C.difficile
happens when someone loses diversity of colon, C.diff outgrowth production of toxins
29
C.diff prodices
antiobiotic associated diarrhea
30
what is pseudomembranous colitis
this is the worse state of C.diff diarhea characterised by inflammatory lesions, perforation and shock
31
what plays a role in Obesity
gut microbiota plays a role because of lack of ability to block fermentation
32
Types of Oral Dysbiosis
Dental caries and periodontitis
33
dental carries
fermentatiion leads to acid production, decrease in diversity
34
Priodontitis
this is inflammation can lead to destruction of gums, bone transplant. decrease in diveristy
35
diffewrence between vaginosis and vaginities
odor, discharge for vaginosis while vaginitis is inflammatory infection
36
What occurs in vaginal dysbiosis
decrease in lactobacillus, growth of candida, trichomonas vaginalis
37
what are probiotic
live microorganisms which, when administere din adewquate amounts, confer a health benefit on host
38
prebiotics
plant nutrient we cannot digest, but fermentative gut nicrobes can
39
synbiotics
probiotic +prebiotic