Lecture 21 - Cognitive Disorders (Addiction) Flashcards

(43 cards)

1
Q

what are the three C’s of that define the phenomenon known as addiction?

A

craving, compulsion, and negative consequences

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2
Q

individuals with addictions suffer from _____ for their addicted substance or behaviour, to the extent that it interferes with their normal activities and commitments

A

craving

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3
Q

addicted individuals develop a _____ and loss of control over regulating their use of the substance or behaviour despite repeated attempts to curb an addiction which clearly has negative consequences

A

compulsion

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4
Q

______ includes compromising one’s work or employment, the pursuit of education and career goals, damage to family relationships, financial problems, injury to one’s integrity and reputation, financial troubles, and crime/legal entanglement

A

negative consequences

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5
Q

according to the DSM-5, substance use disorder is a problematic pattern of use leading to:

A

clinically significant impairment or distress, as manifested by at least two major criteria within a twelve month period

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6
Q

what are the eleven major criteria used to diagnose substance use disorder?

A
  • recurrent substance use in physically hazardous situations
  • recurrent use resulting in failure to meet obligations at work, school, or home
  • excess of time spent to obtain or use or recover from the effects of the substance
  • substance often taken in larger amounts or over longer periods of time than intended
  • persistent desire or unsuccessful efforts to cut use
  • craving
  • continued use despite persistent social or interpersonal problems
  • tolerance
  • losing important social, occupational, or recreational activities
  • withdrawal
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7
Q

a need for markedly increased amount of a drug to achieve intoxication/desired effect

A

tolerance

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8
Q

what is the most commonly used addictive substance?

A

alcohol

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9
Q

what are factors used to evaluate the harm drugs cause to users?

A

physical, psychological, and social

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10
Q

what are factors used to evaluate the harm drugs cause to other non-users?

A

physical, psychological, and social (but in a different way than with users)

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11
Q

substance use disorders are a significant public health problem with possible devastating consequences for:

A

affected individuals, their familes, and society

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12
Q

it is estimated that over ____ of North Americans suffer from a substance use disorder (SUD) at some point in their lifetime

A

18%

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13
Q

at least ____ of medical patients and ____ of psychiatric patients have a concomitant SUD

A

20%, 30%

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14
Q

see slide 654

A

cool diagram (dunno if its important though)

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15
Q

what is the most effective treatment option for SUD?

A

harm reduction (supervised consumption sites, drug substitution, and decriminalization)

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16
Q

the crisis arising from increased rates of opioid misuse has been sttributed to:

A

overprescribing of opioid pain medications (means that when dependent patients are refused a medical prescription they have to turn to street drugs)

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17
Q

SUD is often comorbid with a primary psychitric disorder and may have its origins in:

A

self medication

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18
Q

the most effective way to curtail addiction at an early stage

A

strategic brief intervention and referral to treatment (SBIRT)

19
Q

many drugs of abuse act directly or indirectly at:

A

brain neurotransmitter sites

20
Q

brain systems underlying addiction of all kinds are known to be those involved with control of:

A

motivation, establishment of learned habits, and reward

21
Q

addiction is proposed as a process in the brain with _____ and _____ features; related to approach of _____ experiences and to avoid _____

A

rewarding, aversive, rewarding, withdrawal (unpleasant effects)

22
Q

see slide 658

A

you MUST know that slide

23
Q

caffeine influences glutamate by:

A

modulating its release and activity

24
Q

what is the mechanism of action of caffeine?

A

blocks adenosine receptors (particularly A1)

25
true or false: adenosine A1 receptors normally promote the release of glutamate
false, they inhibit the release of glutamate
26
what is the impact of caffeine on the nucleus accumbens?
caffeine elevates synaptic glutamate in the shell of the nucleus accumbens (which is associated with reward and motivation)
27
what is the major brain circuit currently being studied in addiction?
the mesocorticolimbic dopamine system
28
this ascending system arises in the dopamine cell bodies of the ventral tegmental area and projects to the nucleus accumbens septi
the mesocorticolimbic system
29
see slides 661-665
im going to make some flashcards on these but important to still look
30
true or false: nicotine can depolarize dopamine neruons directly, whereas psychostimulaants like cocain, ecstasy, and amphetamines interfere with dopamine reuptake
true
31
what are the four major types of addiction?
substances, gambling, sex, and internet overuse
32
recreational cannabis is often consumed for its rewarding effects, but high THC products may lead to:
addiction, acute mental health, gastrointestinal, and cardiovascular issues
33
chronic opioid use poses great risks to:
asolescents (impaired learning, increased psychosis, mood disorders, suicidal tendencies)
34
physical health risks such as respiratory issues and fetal growth restiction are linked to:
high THC use
35
medical cannabis shows modest benefits for:
chronic pain, epilepsy, spasticity, and nausea
36
see slide 669
is it important? who the hell knows
37
what is the major difference between THC and cannabidiol (CBD)?
chronic THC use is linked to cognitive impairents and mental health risks, whereas high-dose CBD can cause notable side effects over time
38
marijuana related ER visits are associated with:
71% psychiatric diagnosis
39
since the medical legalization of cannabis, there has been a significant increase in:
recreational use of cannabis
40
cannabis designed for recreational use is increasibgly available to patients with chronic pain who do not find relief with current pharmacological entitied, which:
exposes patients to potential harm
41
recreational and medicinal cannabis are:
irresponsibly overlapped
42
what is the main difference between cannabis for recreational and medicinal use?
THC concentration
43
see slide 680 (might as well glimpse the last couple slides while you're at it
you're all done!