Lecture 21: Neurogenesis 2 Flashcards
What is the NTS important for?
baroreceptor reflex control of blood pressure
What are examples of brain areas that undergo neurogenesis?
the cerebral cortex, striatum / substantia nigra, amygdala and hypothalamus
What are baroreceptors important for?
blood pressure control
Where does most of the evidence come from in regards to determining areas of the brain that undergo neurogenesis?
most of the evidence centres around the detection of BrdU at these ‘neurogenic’ sites
What are the developmental stages of adult neurogenesis?
quiescent radial glia-like cells -> transient amplifying cell -> neuroblast -> migrating neuroblast and immature neuron -> interneurons
Where does neurogenesis occur? What could this mean?
in the NTS
this might mean that there is another mechanism of ‘plasticity’ in a highly conserved autonomic circuit
What do hypertensive rats have greater numbers of?
nascent NTS neurons
Where does adult neurogenesis occur?
in the NTS
What do nascent NTS neurons appear to receive? What are they activated by?
primary afferent input
a baroreceptor challenge
