lecture 22 - immunodeficiency Flashcards
1
Q
What is primary immunodeficiency?
A
Genetic immunodeficiency
2
Q
What is secondary immunodeficiency?
A
Immunodeficiency brought on by drugs, infections, cancer or environmental factors
3
Q
When does primary immunodeficiency usually present?
A
Infancy or childhood if less severe
4
Q
Are inherited immunodeficiency diseases usually recessive or dominant?
A
Recessive (loss of function mutations)
5
Q
What is the most common inherited immunodeficiency disease?
A
IgA deficiency
6
Q
What type of infections are those with antibody deficiencies prone to?
A
Recurrent pyogenic infections
7
Q
What type of infections are those with phagocyte deficiencies prone to?
A
Severe bacterial and fungal infections
8
Q
What immune cell is commonly targeted by immunosupressive drugs?
A
T cells
