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Clin Path 2 - Unit 1 > Lecture 3 > Flashcards

Lecture 3 Flashcards

1
Q

what is hematopoiesis

A

the production of blood cells AND platelets

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2
Q

what is whole blood composed of

A

fluid and cells

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3
Q

what is the fluid part of whole blood called

A

plasma

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4
Q

what makes up the cell component of whole blood

A

RBCs
WBCs
Platelets

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5
Q

what are erythrocytes

A

red blood cells

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6
Q

what are leukocytes

A

white blood cells

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7
Q

five kinds of WBCs (leukocytes)

A

neutrophils
eosinophils
basophils
monocytes
lymphocytes

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8
Q

what are thrombocytes

A

platelets

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9
Q

two categories of white blood cells

A

agranulocytes
granulocytes

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10
Q

what WBCs make up agranulocytes

A

Lymphocytes
Monocytes

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11
Q

what WBCs make up granulocutes

A

Neutrophils
Eosinophils
Basophils

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12
Q

what does morphology mean

A

cellular appearance (shape)

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13
Q

multipotent primitive cells that can develop into all types of blood cells

A

Hematopoietic Stem Cell (HSC)

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14
Q

two locations where Hematopoietic Stem Cells (HSC) can be found

A

bone marrow of the long bones

some in the spleen

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15
Q

any of a number of substances, such as interferon, interleukin, and growth factors, which are secreted by certain cells of the immune system and have an effect on other cells.

A

cytokine

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16
Q

stem cell that produces one of the three mature blood cells

A

Myeloid

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17
Q

stem cell that produces lymphocytes (plasma cells)

A

lymphoid

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18
Q

Production of erythrocytes

A

Erythropoiesis

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19
Q

Production of leukocytes

A

Leukopoiesis

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20
Q

Production of thrombocytes

A

Thrombopoiesis

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21
Q

the cytokine responsible for production of RBCs, produced by the kidneys

A

Erythropoietin (EPO)

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22
Q

RBCs become ________ as they mature, lose their ______ and gain __________

A

smaller
nucleus
hemoglobin

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23
Q

RBC development slide

A
24
Q

immature RBCs

A

reticulocytes

25
Q

thrombopoietin is primarily produced where

A

the liver

26
Q

hematopoietic cells, which are responsible for the production of blood platelets

A

Megakaryocyte

27
Q

fragments of the cytoplasm of megakaryocytes

A

platelets

28
Q

stopping the flow of blood

A

hemostasis

29
Q

stimulates the bone marrow to increase the rate of leukopoiesis

A

leukopoietin

30
Q

Granulopoiesis:

Large with round to oval nucleus, prominent nucleolus, pale gray–blue cytoplasm

A

Myeloblasts

31
Q

Granulopoiesis:

Horseshoe-shaped nucleus with parallel sides

A

Band cells

32
Q

Granulopoiesis:

Nuclei with 2 or more lobes – heads to circulation

A

Segmented granulocytes

33
Q

Most common WBC

Job is to defend the body against bacterial infection

A

neutrophils

34
Q
A

neutrophils

35
Q
A

eosinophils

36
Q
A

basophils

37
Q

Present in low numbers or not at all in healthy animals

Often increases in an animal due to parasitic organisms or allergies

A

eosinophils

38
Q

Rarely seen in healthy animals

Associated with allergic disease and parasitic infections

A

basophils

39
Q

Present in low numbers in peripheral blood
Increase with chronic inflammation
Increase with stress in the dog
Tissue repair
Help regulate immune response
Phagocytosis of dead cells and microorganisms

A

monocytes

40
Q

three kinds of lymphocytes

A

T lymphocytes
B lymphocytes
Natural Killer Cells

41
Q

Functions in acquired immunity (memory)

A

lymphocytes

42
Q

1.

A

erythrocyte

43
Q

2.

A

lymphocyte

44
Q

3.

A

neutrophil

45
Q

4.

A

eosinophil

46
Q

5.

A

basophil

47
Q

6.

A

monocyte

48
Q

7.

A

platelets

49
Q

1.

A

Band neutrophil (leukocyte)

50
Q

2.

A

Eosinophil (leukocyte)

51
Q

3.

A

segmented neutrophil (leukocyte)

52
Q

4.

A

basophil (leukocyte)

53
Q

5.

A

lymphocyte (leukocyte)

54
Q

6.

A

monocyte (leukocyte)

55
Q

what do cells become after it has been stimulated to develop into an erythrocyte

A

rubriblasts

56
Q

what rubriblasts become as they continue to divide (three steps)

A

prorubricytes > rubricytes > metarubricytes

57
Q
A

Clin Path 2 - Unit 1 (13 decks)

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