LECTURE 3 | Hematopoietic Tissue Flashcards

(50 cards)

1
Q

Unique form of Connective tissue

A

Blood

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2
Q

3 Major Cell types

A
  1. Erythrocytes (RBC’s)
  2. Leukocytes (WBC’S)
  3. Thrombocytes (Platelets)
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3
Q

Determine the percentage of each in blood:

• Plasma
• Buffy Coat
• RBC

A

• Plasma = 55%
• Buffy Coat = 1%
• RBC’S = 45%

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4
Q

Blood cell production

A

Hemopoiesis

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5
Q

The site of hemopoiesis occurs in the different sites of the body, depending on the ____________.

A

Stage of development

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6
Q

The sites of hemopoiesis when it is still an embryo is in the ___________ and later in the development of liver, spleen, lymph nodes, and bone marrow.

A

Yolk sac

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7
Q

In the newborn, all bone marrow is _______ and functions in hemopoiesis.

A

Red marrow

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8
Q

All blood cells originate from a common _________ in the red bone marrow that is self-renewing.

A

Stem cell

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9
Q

During hemopoiesis, some lymphoid cells remain in the bone marrow and migrate via bloodstream to lymph nodes and the spleen, where they proliferate and differentiate into _______________, after which they colonize peripheral lymphoid tissues.

A

B-lymphocytes

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10
Q

Other undifferentiated lymphoid cells migrate to Thymus gland, where they proliferate and differentiate into immunocompetent ___________.

A

T-lymphocytes

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11
Q

These 2 lymphocytes both resides in numerous peripheral lymphoid tissues, lymph nodes, and spleen.

A

B and T lymphocytes

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12
Q

Initiate immune response when exposed to antigens

A

B-lymphocytes & T-lymphocytes

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13
Q

B and T lymphocytes has a different protein markers on their cell surfaces, by what means does it allow to be distinguished?

A

By immunohistochemical means

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14
Q

Delivers oxygen from lungs to the tissues

A

Erythrocytes

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15
Q

Facilitates carbon dioxide transport

A

Erythrocytes

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16
Q

• Acts as buffer and regulates hydrogen ion concentration
• Contributes to blood viscosity
• Carries blood group antigens and Rh factor

A

Erythrocytes

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17
Q

A major blood cell type that is subdivided in Granulocytes and Agranulocytes depending on the absence/presence of granules in their cytoplasm.

A

Leukocytes

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18
Q

What are the 3 leukocytes that belong to the Granulocytes group?

A

✓ Neutrophils
✓ Eosinophils
✓ Basophils

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19
Q

Capture and destroy invading microorganisms

A

Neutrophils

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20
Q

Mediators of inflammation

A

Neutrophils

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21
Q

A leukocytes that move to inflamed areas

22
Q

Leukocytes that traps substances

23
Q

Leukocytes that:

• Killing cells, anti parasitic and bactericidal activity
• participating in immediate allergic reactions
• Modulating inflammatory response

24
Q

The Innate Immune System

25
It combat parasites by release of cytotoxic chemicals, which attack the parasite.
Eosinophils
26
What does the eosinophils release to combat a parasite?
Cytotoxic chemicals
27
Serve as the immune surveillance
Basophils
28
Help detect and destroy some early cancer cells
Basophils
29
A leukocytes that release histamine in their granules during an allergic reaction.
Basophils
30
Defends against bacterial or fungal infection
Neutrophils
31
Most commonly released with early acute inflammation
Neutrophils
32
Makes up 60% of total leukocyte count
Neutrophils
33
The life span is about 5 days
Neutrophil
34
These are inflammatory cells
Eosinophils
35
These respond in allergic reactions and parasitic invasions
Eosinophils
36
• These are responsible for allergic reactions • They release histamine which causes vasodilation
Basophil
37
These are known as macrophages which are responsible for phagocytosis of pathogenic cells
Monocytes
38
They present pathogens to T cells which kill them.
Monocytes
39
What are the 2 Leukocytes that falls under the group Agranulocytes?
✓ Lymphocytes ✓ Monocytes
40
Helps the body fight cancer and foreign viruses and bacteria (antigen)
Lymphocytes
41
Helps our immune system remember every antigen it comes in contact with.
Lymphocytes
42
Resides in the blood and tissue to find and destroy germs (virus, bacteria, fungi, protozoa) and eliminate infected cells.
Monocytes
43
A leukocytes that call other WBC's to help treat injury and prevent infection
Monocytes
44
Can be found in blood but not a blood cells
Thrombocytes (Platelets)
45
Smallest, nonnucleated formed elements appear in the blood of all mammals
Thrombocytes
46
Largest cells in the bone marrow
Megakaryocytes
47
Membrane bound cytoplasmic fragments or remnants of megakaryocyte.
Platelets
48
It continually monitor the vascular system and detect damage to the endothelial lining of the vessels
Thrombocytes
49
If there are damage /breaks in the vascular system or in the endothelial lining of the vessels, the platelets will adhere to the damaged site and initiate a highly complex chemical process that produces _________.
Blood clotting
50
• They are enucleated (without nucleus) and stain pink with eosin. • They are uniform in size and measure approximately 7.5 um in diameter, which is the approximate size of the capillaries.
Erythrocytes