Lecture 3A Flashcards

DNA STRUCTURE & FUNCTION (55 cards)

1
Q

JAMES WATSON & FRANCIS CRICK

A

Both: Double helix structure of the DNA

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2
Q

Both: Double helix structure of the DNA

A

JAMES WATSON & FRANCIS CRICK

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3
Q

CRICK

A

Central Dogma and Adaptor hypothesis

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4
Q

Central Dogma and Adaptor hypothesis

A

CRICK

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5
Q

WATSON

A

Erwin Schrodinger’s book “what is life”

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6
Q

Erwin Schrodinger’s book “what is life”

A

WATSON

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7
Q

GENE

A

a unit of heredity

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8
Q

a unit of heredity

A

GENE

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9
Q

GENOME

A

the entire set of genes in an organism; totality of genetic component

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10
Q

the entire set of genes in an organism; totality of genetic component

A

GENOME

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11
Q

LOCUS (LOCI)

A

a fixed location on a strand of DNA where a gene or one of its alleles is located

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12
Q

a fixed location on a strand of DNA where a gene or one of its alleles is located

A

LOCUS (LOCI)

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13
Q

ALLELES

A

two forms of a gene that occupy the same position on homologous chromosomes and that cover the same trait

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14
Q

two forms of a gene that occupy the same position on homologous chromosomes and that cover the same trait

A

ALLELES

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15
Q

DEOXYRIBONUCLEIC ACID (DNA)

A

material basis of heredity

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16
Q

material basis of heredity

A

DEOXYRIBONUCLEIC ACID (DNA)

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17
Q

biological macromolecule for the storage of genetic information

A

DEOXYRIBONUCLEIC ACID (DNA)

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18
Q

DEOXYRIBONUCLEIC ACID (DNA)

A

biological macromolecule for the storage of genetic information

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19
Q

universal for all bacteria, higher organisms

A

DEOXYRIBONUCLEIC ACID (DNA)

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20
Q

DEOXYRIBONUCLEIC ACID (DNA)

A

universal for all bacteria, higher organisms

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21
Q

DNA can be found in

A

– Nucleus (biparental inheritance)
– Plastids (uniparental inheritance)
* Mitochondria: maternal
* Chloroplasts:
> Angiosperms usually maternal
> Gymnosperms (conifers!) usually paternal

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22
Q

– Nucleus (biparental inheritance)
– Plastids (uniparental inheritance)
* Mitochondria: maternal
* Chloroplasts:
> Angiosperms usually maternal
> Gymnosperms (conifers!) usually paternal

A

DNA can be found in

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23
Q

Each nucleotide consists of:

A
  • 5-carbon sugar (deoxyribose),
  • nitrogen containing base attached to the sugar,
  • phosphate group.
24
Q

A forms…

A

2 hydrogen bonds to T,

25
G forms
3 hydrogen bonds to C
26
PURINE BASES (A and G)
larger of the two types of bases found in DNA
27
larger of the two types of bases found in DNA
PURINE BASES (A and G)
28
PYRIMIDINES (C and T)
The 6 atoms (4 carbon, 2 nitrogen) are numbered 1-6. Like purines, all pyrimidine ring atoms lie in the same plane
29
The 6 atoms (4 carbon, 2 nitrogen) are numbered 1-6. Like purines, all pyrimidine ring atoms lie in the same plane
PYRIMIDINES (C and T)
30
RIBOSE
a sugar, like glucose, but with only five carbon atoms in its molecule
31
a sugar, like glucose, but with only five carbon atoms in its molecule
RIBOSE
32
DEOXYRIBOSE
almost the same but lacks one oxygen atom
33
almost the same but lacks one oxygen atom
DEOXYRIBOSE
34
The deoxyribose, the phosphate and one of the bases combine to form a nucleotide
NUCLEOTIDES
35
NUCLEOTIDES
The deoxyribose, the phosphate and one of the bases combine to form a
36
DOUBLE HELIX
bases and sugar-phosphate chain
37
bases and sugar-phosphate chain
DOUBLE HELIX
38
characteristics of DNA (DNA vs RNA)
Double stranded A pairs with T G pairs with C Resides in nucleus
39
Double stranded
DNA
40
A pairs with T
DNA
41
Resides in nucleus
DNA
42
G pairs with C
DNA
43
characteristics of RNA (DNA vs RNA)
Single stranded A pairs with U G pairs with C Resides in nucleus and cytoplasm
44
DNA OF THE NUCLEUS
- Can be measured in base pairs since it is a double stranded molecule - Higher organisms: 108 to 1011 base pairs - Plants: particularly variable genome size > Conifers: large - Repetitive sequences (102 to 108) - Many sequences without known function - Note: Genome of complex organism is not necessarily larger than simple organisms
44
DNA OF PLASTIDS
Chloroplast DNA: cpDNA Mitochondrial DNA: mtDNA
45
Chloroplast DNA: cpDNA
Approximately 120,000 – 200,000 bps
46
Approximately 120,000 – 200,000 bps
Chloroplast DNA: cpDNA
47
Completely sequenced for several plants
Chloroplast DNA: cpDNA
48
Chloroplast DNA: cpDNA
Completely sequenced for several plants
49
Pinus thunbergia
Chloroplast DNA: cpDNA (example)
50
Chloroplast DNA: cpDNA (example)
Pinus thunbergia
51
Mitochondrial DNA: mtDNA
Approximately 16,000 bps (human)
52
Approximately 16,000 bps (human)
Mitochondrial DNA: mtDNA
53
Mitochondrial DNA: mtDNA
Sequenced for human, some animals
54
Sequenced for human, some animals
Mitochondrial DNA: mtDNA