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COM: Immunology (Midterm) > Lecture 4&6: Lymphoid Tissue I & II > Flashcards

Lecture 4&6: Lymphoid Tissue I & II Flashcards

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1
Q

What is the arrow pointing at and where would you find this tissue?

A

Arrow is pointing at CT and this is GI tissue

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2
Q

What is the arrow pointing at and where would you find this tissue?

A

The airway is pointing at CT and this is airway tissue

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3
Q

What is this a picture of?

A

Primary nodule (singular nodular tissue - non-encapsulated lymphoid tissue)

  • Far more infrequent than secondary nodules
  • Consist of only small lymphocytes
  • Prenatal
  • do not possess a germinal center
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4
Q

What is the circle and the 2 arrows in this picture?

A

Circle = secondary lymphoid nodule (singular nodular tissue, non-encapsulated lymphoid tissue)

Left arrow = mantle zone

Right arrow = germinal center

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5
Q

What is this a picture of?

A

Secondary lymph nodule

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6
Q

What is this a picture of?

A

Primary lymph nodule

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7
Q

Name the 3 tonsils in the picture

A

Top = pharyngeal tonsil (adenoids)

Middle = palatine tonsils

Bottom = lingual tonsils

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8
Q

What type of tonsil is this and what are the 2 arrows indicating?

A

Pharyngeal tonsil

Top arrow = pseudostratified columnar ciliated epithelium

Bottom arrow = germinal center

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9
Q

What type of tonsil is this and what are the arrows indicating?

A

Palatine tonsil

Top arrow = stratified squamous epithelium

next = partial capsule

Next = germinal centers

Bottom = crypts

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10
Q

What is this a picture of and what do the arrows indicate?

A

Lingual tonsil

Top arrow = stratified squamous epithelium

Bottom arrow = one crypt per tonsil

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11
Q

What is this a picture of?

A

Palantine tonsil

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12
Q

What is this a picture of?

A

Lingual tonsil

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13
Q

What is this a picture of?

A

Pharyngeal tonsil

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14
Q

What do the arrows in this picture indicate?

A

Left = ileum

Middle = villi

Right = lymphoid tissue

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15
Q

What does the box in this picture indicate?

A

GALT -> AKA Peyers patches

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16
Q

Where is this tissue found?

A

Small intestine

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17
Q

Where is this tissue found?

A

Vermiform appendix

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18
Q

Where is MALT found?

A

GI tract, respiratory passageways and urinary tract

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19
Q

GALT is called Peyers patches in the ileum and is characterized by an abundance of ______

A

Villi

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20
Q

GALT in the vermiform appendix is characterized by crypts and no ______

A

villi

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21
Q

How many palatine tonsils does a person have

A

2

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22
Q

How many pharyngeal tonsils does a person have

A

1

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23
Q

How many lingual tonsils does a person have?

A

Small and numerous

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24
Q

Where are palatine tonsils found?

A

Lateral walls of oral cavity

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25
Where are pharyngeal tonsils found?
Posterior of nasopharynx
26
Where are lingual tonsils found?
Posterior third of tongue
27
How many crypts are found in palatine tonsils?
Many! 10-20
28
How many crypts are found in pharyngeal tonsils?
None
29
How many crypts are found in lingual tonsils?
1
30
What type of epithelium are palatine tonsils?
non-keratinized stratified squamous
31
What type of epithelium is found in pharyngeal tonsils?
Ciliated pseudustratified columnar
32
What type of epithelium is found in lingual tonsils?
Stratified squamous
33
Which lingual tonsil has a thick capsule?
Palantine tonsil
34
What tonsil has a thin capsule?
Pharyngeal tonsil
35
What tonsil has no difinitive capsule?
Lingual
36
What is this an image of?
The thymus pre-puberty
37
What is this an image of?
The thymus post-puberty
38
Label the arrows in the picture
Top arrow = cortex Next = medulla Next = capsule Bottom arrow = septum
39
Label the arrows in the image
Top = cortex Bottom = Septum
40
What structure is in this picture and where, in what organ is it found?
Hassels corpuscles found in the thymus -\> ONLY in the medulla
41
What type of tissue is this and where is it found?
Capsulated lymphoid tissue in the thymus
42
Label the arrows in this picture
Top = capsule Next = cortex Next = medulla Last = Hassals corpuscle
43
What organ is this?
Spleen -\> no lobules
44
Where is this tissue found?
Spleen
45
Label A-D of the splenic tissue
A) Capsule B) Trabecula C) Red pulp D) White pulp
46
Label 1-5
1) germinal center 2) corona 3) marginal zone 4) periarteriolar lymphoid sheath 5) central arteriole
47
Label the arrows of the splenic tissue
Both are marginal zones
48
Label the arrows of the splenic tissue
Top = splenic cord Bottom = splenic sinusoid
49
Label the arrows of the splenic tissue
Top = splenic cord bottom = splenic sinusoid
50
51
Label A-E
A) Germinal center B) Mantle C) Lymphatic nodule D) Inner cortex E) Outer cortex
52
Where would you find this tissue?
Lymph node
53
Label the arrows and state where you would find this tissue
Top = medullary sinus Bottom = medullary cord This tissue is found in the lymph nodes
54
Label A-C
A) Capsule B) Cortex C) Medulla
55
Label D-F
D) Germinal center E) Mantle F) Lymphatic nodule
56
Label G-I
G) Medullary sinus H) Medullary cord I) Hilum
57
Where is this tissue found? Is there a capsule, lobules, cortex, or medulla?
lymph node: capsule, cortex and medulla, but no lobules
58
What is this structure?
Lymph node
59
What structures are seen here?
Hassels corpuscles of the thymus
60
What is this structure?
The appendix
61
What is this structure?
A primary nodule
62
What structures lymphoid structures are capsulated?
Thymus, spleen and lymph nodes
63
Of the capsulated lymphoid organs, which are lobulated and which arent?
Lobules = thymus No lobules = spleen, lymph nodes
64
What capsulated lymphoid organ decreases in size with age?
Thymus
65
The thymus is the only capsulated lymphoid organ that is lobulated. How many lobules does it possess?
2
66
What structure does the medulla of the thymus contain?
Hassals corpscles
67
Does the thymus contain germinal centers?
No!
68
What cell types does the cortex of the thymus contain?
Subscapular thymic epithelial cells Thymic cortical epithelial cells Maturing T cells (developing thymocytes)
69
What cell types are found in the medulla of the thymus?
Hassals corpuscles Thymic medullary epithelial cells Dendritic cells
70
Are macrophages present in the thymus?
Yes! Present in both the cortex and the medulla
71
What is the site of mature lymphocytes in the thymus?
Medulla
72
How does the staining differ between the cortex and the medulla?
Cortex = darker Medulla = lighter
73
What is the role of hassals corpuscles?
Release a factor that stimulates thymic DCs to complete maturation of T cells
74
Where is the thymus-blood barrier found and what is its role?
Only exists in the cortex and prevents most circulating Ags from reaching developing T cells
75
What is the role of macrophages in the spleen?
Destroy old RBCs
76
\_\_\_\_\_\_\_\_\_\_\_ extend from the capsule and divide the spleen into incomplete compartments
Trabeculae
77
Does the spleen contain a cortex or medulla?
No
78
What is the white pulp of the spleen rich in?
Lymphoid tissue
79
What is the red pulp of the spleen rich in?
RBCs
80
What cell types are found in the corona of the spleen?
B cells and APCs
81
What is the marginal zone of the spleen?
Where red and white pulp interact
82
What cell type is found in the periarteriolar lymphoid sheath?
T cells
83
The ________ arteries and the small capillaries of the spleen that they produce are sheathed by macrophages, that are responsible for removing damaged RBCs and particles from the blood
penicillar
84
Central arteries leave the white pulp and enter the red pulp as ___________ arteries, which either end in the splenic _________ (closed circulation) or into the ______________ (open circulation)
penicillar; sinusoids; red pulp
85
\_\_\_\_\_\_\_\_\_ arteries produce radial arteries while in the white pulp that feed into the marginal zone sinuses
Central
86
\_\_\_\_\_\_\_\_ arteries divide into central arteries which penetrate the white pulp and are surrounded by periarteriolar lymphoid sheaths
trabecular
87
\_\_\_\_\_\_\_\_\_ artery divides into trabecular arteries which follow the trabeculae into parenchyma of the spleen
Splenic
88
What are the smallest, most numerous encapsuated lymphoid organs?
lymph nodes
89
What cell type is the outer cortex of LNs rich in?
B cells
90
What cell type is the inner cortex rich in?
T cells
91
What cell types is the medullary cords of LNs primarily made up of?
Macrophages and plasma cells
92
Where is the lymph cleared of 90% of Ags and cellular debris?
THe sinuses of the LNs
93
What are medullary sinuses?
Found in LNs -\> spaces lined by endothelial cells surrounded by reticular cells and macrophages
94
Out of the lymphoid organs: thymus, LNs, spleen, and tonsils, which have a cortex and medulla?
thymus and LNs
95
Out of the lymphoid organs: thymus, LNs, spleen, and tonsils, which have lymphoid nodules?
LNs, spleen, tonsils
96
Out of the lymphoid organs: thymus, LNs, spleen, and tonsils, which have cords and sinuses?
LNs and spleen
97
WHat is the diagnostic feature of the thymus?
Hassalls corpuscles
98
What is the diagnostic feature of the LNs
Cortical nodules and subcapsular sinus
99
What is the diagnostic feature of the spleen?
Central arteries
100
What is the diagnostic feature of the tonsils
epithelial covering

COM: Immunology (Midterm) (9 decks)

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