Lecture 5: histo + structure Flashcards Preview

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Flashcards in Lecture 5: histo + structure Deck (32):
1

What kind of epithelium is found in the intestine?

simple columnar

2

What kind of epithelium is found in the oral cavity and esophagus?

stratified squamous epithelium
non-keratinized

3

What is the difference between the epithelium of the facial skin and oral mucosa?

facial skin (outside of lip) = keratinized, squamous
oral mucosa (inside of lip) = stratified squamous, non-keratinized

4

What parts of oral cavity are keratinized?

gingiva, hard palate, filiform papillae

5

which lingual papillae do not have taste buds?

filiform

6

which lingual papillae are keratinized?

filiform

7

What is the epithelium of the stomach?

simple columnar

8

What kind of cell types are in gastric epithelium?

Surface mucuous cell
Mucous neck cell
Parietal cell
Chief cell
Enteroendocrine cell

9

What do each of these cells secrete?

Mucous cells = mucus
Parietal cell = H+, Cl-, IF
Chief cell = pepsinogen, lipase
Enteroendocrine cell = gastrin, histamine, somatostatin

10

What is the function of surface mucous cells in the stomach?

mucin production to protect against gastric contents (acid)

11

What's another name for gastric parietal cells?

oxyntic

12

What is the function of gastric parietal cells?

production of HCl and intrinsic factor

13

What is the function of gastric chief cells?

produce pepsinogen and lipase

14

What are functions of the small intestine?

digest carbs, proteins + lipids
nutrient absorption
neutralize gastric acid
absorb bile acids
produce GI regulators
immune defense

15

What kind of epithelial cells are in the small intestine?

goblet cells
enteroendocrine cells
paneth cells
enterocytes

16

What are the functions of enterocytes in the small intestine?

absorptive cells: make up majority!
nutrient digestion (brush border = villi)
conditional electrolyte secretion

17

What are the functions of the goblet cells in the small intestine?

produce mucus for protection of epithelium (from, for example, microbes)

18

What do enteroendocrine cells (EEC) do in the small intestine?

secrete GI regulators: serotonin, CCK, secretin, somatostatin, motilin, GIP...

19

What do paneth cells in the small intestine do?

secrete antimicrobial factors (lysozyme, secreted phospholipase)
Produce growth factors for epithelial stem cells in crypts

20

Where are Brunner's glands located?

duodenum

21

what do Brunner's glands in the small intestine do?

secrete:
mucin
bicarbonate
epithelial protective factors

22

What is the function of the iliocecal junction?

prevents reflux of colon contents into ileum

23

What cell types are in the colon?

absorptive cells
EEC cells
Goblet cells

24

What kind of epithelium lines the rectum? What kind lines the anal canal and the perianum?

rectum = simple columnar
anal canal = stratified squamous, nonkeratin
perianum = stratified squamous, keratinized

25

What segments of the GI tract contains parietal and chief cells?

stomach corpus/fundus
stomach antrum (minor)

26

What segments of the GI tract contains mucous cells?

stomach corpus/fundus
stomach antrum

27

What segments of the GI tract contains enterocytes/absorptive cells?

duodenum
jejunum/ileum
colon

28

What segments of GIT contains goblet cells?

duodenum
jejunum/ileum
colon

29

what segments of GIT contains paneth cells?

duodenum
jejunum/ileum

30

What are chief products of EEC cells in the stomach

gastrin
Histamine
somatostatin
ghrelin

31

what are chief products of EEC cells in the small intestine?

cholecystokinin
secretin
glucose dependent insulinotropic peptide (GIP)
Motilin

32

what are products of EEC cells in the colon?

serotonin
glucagon-like peptides (GLP)
peptide tyrosine tyrosine
somatostating