Lecture 6

Question 1

What oxygen use class is Strep Pyogenes found in?

Answer 1

Strep Pyogenes is a MicroAeroPhilic bacterium

Question 2

Can Strep use Oxygen?

Answer 2

NO, MicroAeroPhilic=no Resp!!

Question 3

What does the word Pyogenic mean?

Answer 3

Pyogenic= “Pus Forming”

Question 4

What does a decorated crab have to do with Strep pyogenes?

Answer 4

It can disguise itself from our immune sys

Question 5

What is the END result of superantigen of Strep Pyogenes?

Answer 5

Scarlet Fever

Question 6

What is another name for enzymes secreted by both strep and staph causing cellulitis?

Answer 6

F.E.B.!!! Flesh Eating Bacteria

Question 7

What are the three ways we can classify a Strep member?

Answer 7

1.Hemolysis (beta, alpha, gamma) 2.Its Lancefield CHO Antigens (A,B) 3. Its Natural Clusters/loactions

Question 8

What is the beta-hemolytic strep’s affect on RBCs?

Answer 8

COMPLETE hemolysis

Question 9

What is the alpha-hemolytic streps affect on RBCs?

Answer 9

Changes Hemoglobin shape and therefore changes its color to GREEN!

Question 10

What is the gamma-hemolytic strep affect on an RBC?

Answer 10

NOTHING!

Question 11

S. Lactis =

Answer 11

Lactics Strep

Question 12

E. Fecalis, E. Faecium, E. Bovis, E. Swis=

Answer 12

Enterococci Strep

Question 13

S. Pyogenes, S. Agalactiae, S. Pneumonia=

Answer 13

Pyogenic Strep

Question 14

S. Mitis, S. Salivarius, S. Mutans=

Answer 14

Viridans Strep

Question 15

What are the MAJOR bacterial species found in the oral cavity?

Answer 15

alpha-hemolytic viridans strep

Question 16

What is G.A.S. (group-a-strep), has many toxins, and causes step throat, rheumatic fever, cellulitis, and scarlet fever?

Answer 16

Strep Pyogenes

Question 17

What is Beta-hemolytic, has a Capsule, and causes neonatal sepsis (birth canal flora)? (hint: battle star galactitca)

Answer 17

S. Agalactiae

Question 18

What is alpha-hemolytic, has a capsule, and causes MENINGITIS, pneumonia, and ear infections?

Answer 18

S. Pneumoniae

Question 19

What is alpha-hemolytic and can cause SUB-acute endocarditis, caries?

Answer 19

Viridans strep

Question 20

Which hypersensitivity type is most serious?

Answer 20

Type I

Question 21

How would repeated Strep occur?

Answer 21

The M protein presented by Strep becomes altered

Question 22

What are cyclic toxins produced by strep that can kill leukocytes?

Answer 22

Strepto-Lysin

Question 23

How can strep INACTIVATE the C5a “911” molecule?

Answer 23

Using C5a peptidase

Question 24

What are the THREE approaches for strep to damage the host?

Answer 24

1.Pyogenic Infection 2.Toxic Systemic 3.Immune Sequelae Disease

Question 25

What is the skin manifestation of BOTH Strep AND Staph pyogenic infection?

Answer 25

Impetigo

Question 26

What are the three main strep pyogenic/LOCAL infections?

Answer 26

Strep Throat, Impetigo, and Cellulitis

Question 27

What are the two main toxic systemic diseases of strep?

Answer 27

Scarlet Fever and Strep Toxic Shock Syndrome (STSS)

Question 28

What are the two main Sequelae diseases of strep? What are their sensitivity types?

Answer 28

Rheumatic Fever (Type II), and Glomerulonephritis (Type III)

Question 29

Which of the three exotoxin classes is at the root of Scarlet Fever and Strep Toxic Shock-LIKE Syndrome? (end result is a cytokine storm)

Answer 29

Superantigen! (Toxin "glues" TCR's to Class II MHCs)

Question 30

Which Type of hypersensativiy has to do with the coke bottle and the water bottle looking similar and therefore the body mounts a response agains both pathogen and self receptors?

Answer 30

Type II.....Think Two bottles!

Question 31

What type of hypersensitivity is caused by the formation of complexes that can gather "like leaves on the storm drain during the fall?" (which then macrophages come and indescriminantly eat)

Answer 31

Type III...Think Fall is the third season

Question 32

Which is generally more resistant to antibiotics: strep or staph?

Answer 32

Staph is generally more resisstant

Question 33

NO CARDS ON ACUTE VS SUBACUTE

Answer 33

MAKE SOME LATER?