Lecture 6 Flashcards

Cell Metabolism II (37 cards)

1
Q

proteins

A

the basis of cellular function

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2
Q

what are proteins made of

A

collagen, elastin, tubulin

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3
Q

functions of proteins

A

cell structure, enzymes, antibodies, hormone receptors, transports proteins, ion channels

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4
Q

nucleotides

A

the gene sequence blocks for each protein

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5
Q

coding region

A

DNA nucleotide sequence doing for the amino acid sequence of the protein

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6
Q

regulatory regions

A

DNA nucleotide sequences that regulate the expression of the gene (turned on or off)

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7
Q

regulatory regions

A

DNA nucleotide sequences that regulate the expression of the gene (turned on or off)

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8
Q

what makes up nucleotides

A

one nitrogenous base, pentose, and a phosphate group

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9
Q

DNA

A

two strands, double helix, deoxyribose

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10
Q

RNA

A

single strand, pentose is ribose

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11
Q

mRNA

A

messenger RNA

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12
Q

mRNA

A

messenger RNA; copies the anti-sense strand and takes it from the nucleus to the cytoplasm

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13
Q

rRNA

A

ribosomal RNA; from ribosomes attaching to mRNA, completes protein synthesis

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14
Q

tRNA

A

transfer RNA; transports mRNA from nucleus to cytoplasm

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15
Q

example of a gene sequence

A

TAC CCG AGG CGT CCG AAA

made of nucleotides

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16
Q

codon

A

three nucleotides to code for an amino acid

17
Q

sense strand

A

coding strand, the complement to the anti-sense strand (what you start with)

18
Q

anti-sense strand

A

DNA strand used for protein synthesis

19
Q

codon

A

three nucleotides to code for an amino acid

20
Q

transcription

A

in a nucleus; DNA double helix unwound, RNA polymerase binds to the anti-sense strand, RNA polymerase tracks along the DNA strand, runs of the complementary strand of mRNA

21
Q

translation

A

in the cytoplasm; requires messenger RNA, ribosomes, transfer RNAs, amino acids, ATP

22
Q

start codon

A

AUG/methionine

23
Q

anticodon

A

binds to the mRNA codon for the amino acid

24
Q

stop codon

25
chaperones
ensures proteins are folded correctly
26
ubiquitin
labels incorrectly folded protein for destruction
27
proteasome
transforms incorrectly folded proteins into individual amino acids
28
autophagy
the process of destroying damaged proteins and other organelles; involves cell's lysosomes
29
gene therapy
DNA carrying a normal gene incorporated into the patient's cell
30
diploid
somatic cells, cells that have two sets of chromosomes
31
somatic
cells two sets of chromosomes (body cells)
32
mutation
a defective protein that often results in the genetic disease
33
types of mutations
1. the incorrect pairing of bases in DNA replication 2. insertions of extra bases or deletion of a base during replication 3. expansion in the numbers of trinucleotide repeats, Huntington's disease 4. whole sections of deleted, reverse, or transposed DNA
34
engineered viruses
vectors transfer copies of the normal gene into a patient's cells
35
liposomes
lipid bilayer sphere incorporate the DNA into liposomes
36
DNA profiling
forensic application, the study of human evolution
37
polymerase chain reaction
makes million sof copies of short tandem repeat sections