lecture 6 (respiratory) Flashcards

(29 cards)

1
Q

what is polysomnography?

A
  • sleep study taken to test for sleep disorders
  • measures brain waves, oxygen levels in blood, heart rate and breathing
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2
Q

what is REM sleep?

A
  • rapidly movement sleep
  • where memory consolidation occurs
  • hypotonia of skeletal muscles
  • only diaphragm working
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3
Q

what occurs in slow wave sleep?

A
  • voluntary muscle paralysis
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4
Q

what occurs to sleep as you age?

A
  • need less sleep
  • decreased slow wave sleep
  • increased awakenings
  • decreased melatonin
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5
Q

what two processes govern sleep and wakefulness?

A
  • homeostatic sleep drive
  • intrinsic circadian rhythm
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6
Q

what is homeostatic sleep drive?

A
  • messages from brain increase desire to sleep as awake longer
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7
Q

what is intrinsic circadian rhythm?

A
  • biological clocks
  • alert in the day, less alert at night
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8
Q

what occurs in obstructive sleep apnoea?

A
  • airway is partially or completely blocked
  • cessation of airflow but continuing effort
  • ribcage moving but no airflow
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9
Q

what occurs as a result of obstructive sleep apnoea?

A
  • decreased saturation of haemoglobin
  • haematological changes
  • oxygen saturation decreases
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10
Q

what is central sleep apnoea?

A
  • no effort to breathe
  • neurological
  • ribcage isn’t moving
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11
Q

what are the causes of central sleep apnoea?

A
  • periodic breathing
  • cheyne stokes respiration
  • LVF
  • neuromuscular disease
  • altitude
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12
Q

what is the pathophysiology of obstructive sleep apnoae?

A
  • periods of cessation of breathing despite efforts to breathe
  • decreased pharyngeal tone
  • pharyngeal collapse
  • causes daytime sleepiness, snoring, oxygen desaturation
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13
Q

where is the main area of airway collapse in obstructive sleep apnoea?

A
  • pharyngeal muscles
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14
Q

what MRI images are shown during apnoea?

A
  • awake = air column fully open
  • asleep = air column collapsed behind tongue
  • asleep = ar column collapsed from uvular to larynx
  • awake = air column fully open again
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15
Q

what occurs to oxygen saturation levels throughout the night in OSA?

A
  • decreases
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16
Q

what occurs to pulse rate in the night in OSA?

A
  • episodic rise in pulse rate with each arousal from sleep
17
Q

what are the predisposing factors of OSA?

A
  • obesity
  • weight loss
  • large neck size
18
Q

how is sleep apnoea measured?

A
  • apnea-hypopnea index
  • number of apnea events divided by number of hours of sleep
19
Q

how does retrognathia cause OSA?

A
  • smaller retroglossal airway
  • usually have smaller jaws
  • teeth removed to maximise airflow inside
20
Q

what features develop likelihood of OSA?

A
  • enlarged tonsils
  • small jaw
  • elongated soft palate
21
Q

what are the symptoms of OSA?

A
  • loud snoring
  • gasping
  • chocking
  • stopping breathing
  • daytime sleepiness
22
Q

what is the treatment fr OSA?

A
  • weight loss
  • improved diet, excersize, medications
  • sleep hygiene (positional changes, avoidance of sedatives)
23
Q

what is CPAP?

A
  • nasal continuous postiive airway pressure
  • mask used overnight to help breathing
24
Q

what does CPAP do?

A
  • forces airway open
  • supports airflow
25
what are some non respiratory sleep disorders?
- insomnia - circadian rhythm disorders (dysregulted brain rhythm) - too much sleep - sleep walking
26
assess this case: - 33 year old - falling asleep all the time - refreshed by micro naps - episodes of feeling jelly like when laughs hard - sleep paralysis episodes - some dream recall
- narcolepsy
27
what is narcolepsy?
- excessive sleepiness due to neurological condition - caused by failure of neurotransmission in brain neurones (orexin/hypocretin)
28
what are the orexin/hypocretin neurones important for?
- brain alertness - control of muscle tone
29
what is REM sleep behaviour disorder?
- occurs in middle aged to elderly males - progressive - normal REM atone leading to acting out of dreams - change in dream content - association with Parkinsons disease and related disorders - treated with clonazepam