LECTURE 68 - nausea & vomiting Flashcards

(32 cards)

1
Q
A
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2
Q

Define nausea

A

Sickness at the stomach, an inclination to vomit

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3
Q

Define vomiting

A

The ejection of matter forcibly from the stomach through the esophagus and mouth

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4
Q

Define retching

A

Making movements of vomiting without effect

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5
Q

List CNS disorders that could cause N/V

A

Influenza
Intestinal pathogen
Ulcers; GERD
Pancreatitis
Cholecystitis
Obstruction
Tumors
DM gastroparesis

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6
Q

List CNS disorders that could cause N/V

A

Anxiety
Tumors
HA

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7
Q

List treatment-induced causes of N/V

A
  • cancer chemotherapy
  • radiation therapy
  • anesthesia
  • procedures (esp. abdominal)
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8
Q

List drug-induced causes of N/V

A
  • Anti-neoplastic agents
  • Opioids
  • Aspirin, NSAIDs, etc
  • Iron
  • Some antibiotics (tetracycline, erythromycin)
  • Estrogens (high doses)
  • Anti-Parkinson’s meds
  • SSRIs
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9
Q

List possible complications of N/V

A
  • Patient discomfort
  • Dehydration (K, Na, Cl)
  • Malnutrition
  • Aspiration Pneumonia
  • Anxiety (anticipatory N/V)
  • Compromise therapy
  • Decreased QOL
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10
Q

What should be considered when assessing N/V?

A
  • Number of episodes
  • Onset
  • Duration of symptoms
  • Evidence of dehydration
  • Severity of nausea (visual analog scale → 0-10)
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11
Q

Describe the first steps for treating N/V

A

Determine the cause

Put the gut to rest:
Clear liquid diet
IV hydration

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12
Q

What dietary recommendations should be given to a pt experiencing N/V?

A

Avoid fatty, fried, sweet & spicy foods
Eat food that is cold or at room temp

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13
Q

What are some physical non-pharm options to “treat” / prevent N/V?

A
  • Avoid unpleasant sights, sounds & odors that may aggravate NV
  • Fresh air
  • Avoid sudden movements
  • Dim lights

ReliefBand

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14
Q

Describe the ReliefBand

A
  • Acupressure
  • 3 fingers above the wrist
  • Helps the stomach return to a normal rhythm of 3 cycles/min
  • Pregnancy, chemotherapy
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15
Q

What is key to the treatment of motion sickness?

A

PREVENTION

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16
Q

List treatment options for motion sickness

A
  • Transderm-Scop (scopolamine)
  • Dramamine (dimenhydrinate 50 mg)
  • Bonine, Dramamine Less Drowsy, Zentrip (meclizine 25 mg)
17
Q

Describe the dosing for Transderm-Scop (scopolamine)

A

Apply patch BEFORE needed
Duration = 72 hours

18
Q

Describe the dosing for Dramamine (dimenhydrinate 50 mg)

A

Use 30-60 minutes BEFORE needed
Oral

19
Q

Describe the dosing for Bonine, Dramamine Less Drowsy, Zentrip (meclizine 25 mg)

A

Use 30-60 minutes BEFORE needed
Oral

20
Q

List treatment options for N/V secondary to gastroenteritis / pain

A

treat the symptoms while treating the cause

Ondansetron
Promethazine

21
Q

Describe ondansetron as a treatment option for N/V secondary to gastroenteritis / pain

A

4-8 mg IV/ODT/PO
q8-12h PRN

22
Q

Describe promethazine as a treatment option for N/V secondary to gastroenteritis / pain

A

12.5 - 25 mg IV/IM/PO
q4-6h PRN

23
Q

What pt specific factors contribute to post-op n/v (PONV)?

A

F > M
Non-smoking status
Hx of PONV
Hx of motion sickness

24
Q

List risk factors for PONV

A

Intra-operative use of volatile anesthetic
(less with propofol)

Use of nitrous oxide

Types of surgery:
Laparoscopy
Craniotomy
ENT

25
What is the best way to treat PONV?
PREVENTION
26
List treatment options for pts with low risk of PONV & 0-1 risk factors
No tx necessary
27
List treatment options for pts with mod-high risk of PONV & 2+ risk factors
- tx w/ 1 or 2 agents - only 1 agent if propofol is used - 5-HT3 antagonists are drug of choice (DOC) - ALL classes can be used - **Drugs administered at end of procedure**
28
List treatment options for pts with highest risk of PONV & 3+ risk factors (especially hcx of PONV)
- ALWAYS use 2 agents - 5-HT3 & metoclopramide or aprepitant
29
List treatment options for breakthrough PONV
Use an agent from a different class if w/in 6 hours of original dose Amisulpride (Barhemsys) 5-10 mg IV infused over 1-2 minutes
30
When should Emend (aprepitant) be administered for treatment of PONV (dosing)?
40 mg PO 1-3 hours PRIOR to induction of anesthesia
31
What should be monitored to determine efficacy of antiemetic therapy?
Frequency & duration Nausea rating Ability to eat PRN doses of anti-emetic agents QOL ratings
32
What should be monitored to determine potential toxicity of antiemetic therapy?
Sedation / drowsiness Dizziness Diarrhea Headache Anticholinergic SE Extrapyramidal symptoms (EPS)