Lecture 7

Question 1

Synthetic genetic array analysis tells us more than knockout genes

Answer 1

True

Question 2

Genetic interaction networks tell us which genes act to work together

Answer 2

True

Question 3

We create mutations in RNAi

Answer 3

False. We replicate null mutations

Question 4

RNAi prevents a sequence of interest being translated

Answer 4

True

Question 5

RNAi is non reversible

Answer 5

False. It can be reverse as we don’t mess with the genome

Question 6

Dicer cleaves dsRNA into smaller fragments

Answer 6

True

Question 7

One plasmid is needed to produce double stranded RNA.

Answer 7

False. Two are needed

Question 8

One form of chemotherapy is to knockout one of the two pathways that depend on each other.

Answer 8

True

Question 9

Trans genesis introduced a indigenous gene

Answer 9

False. It introduces an exogenous gene

Question 10

All offsprings take up transgenes

Answer 10

False. The genetic information may have been destroyed or not taken up initially

Question 11

Sites of basic transgenesis are unpredictable

Answer 11

True

Question 12

Basic transgenesis is more effective than the use of embryonic stem cells to generate a transgenic mouse

Answer 12

False. It’s the other way around.