Lecture 8 Flashcards
(11 cards)
1
Q
The thoracic duct and the right lymphatic duct empties into which two main veins?
A
-left (thoracic) and right (lymphatic) subclavian veins
2
Q
(T/F) T cells outnumber B cells by 5x and CD4/CD8 T cell ratio is about 2
A
True
3
Q
network of spony bone partitions
A
trabeculae
4
Q
bone marrow consisting of fat cells
A
yellow marrow
5
Q
erythrocyte and leukocyte containing marrow
A
red marrow
6
Q
Mature B cells express which immunoglobulins?
A
IgM and IgD
7
Q
How long does T cell maturation take?
A
3 weeks
8
Q
Which cells are mostly found in the three concentric layers of the lymph node:
- outer cortex
- parafollicular cortex
- inner medulla
A
- outer cortex- B lymphocytes
- parafollicular cortex-T lymphocytes and APCs
- inner medulla-macrophages, B and T lymphocytes, and plasma cells
9
Q
thymic involution
A
thymus decreases output of naive T cells
10
Q
What are some effects of aging on the immune system?
A
- thymic involution
- increase in ratio of yellow marrow to red marrow
- decrease in naive B and T cells causes increase in memory B and T cells
- increase in autoimmunity
11
Q
immune senescence
A
lower ability to mount immune responses to microbial infections and to vaccines
