Lecture for Ch 10.1: Taste and Smell Flashcards

1
Q

What are taste buds made of?

A

50-100 specialized epithelial cells with long microvilli that extend out of taste bud pore

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2
Q

Types of papillae on tongue

A

1) fungiform
2) circumvallate
3) foliate

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3
Q

Fungiform Papillae

A

on the anterior surface of the tongue, innervated by the facial nerve

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4
Q

Circumvallate Papillae

A

on the posterior surface of the tongue, innervated by the glossopharyngeal nerve

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5
Q

Foliate Papillae

A

on the side of the tongue innervated by the glossopharyngeal nerve

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6
Q

Taste Pathways

A

facial & glossopharyngeal –> medulla oblongata –> thalamus –> primary gustatory cortex of insula/somatosensory lobe/prefrontal cortex

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7
Q

What part of the taste bud comes in contact with chemicals?

A

microvilli

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8
Q

True/false: each taste buds has sensory cells for each taste category

A

TRUE

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9
Q

Taste is influenced by the _____ and _____ of the substance

A

temperature; texture

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10
Q

How does salty reception work?

A

Na+ received by the hair cell through ion channels, causes depolarization, opens Ca channels to release NT to the synapse for the facial or glossopharyngeal nerve to receive stimulation

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11
Q

How does sour reception work?

A

H+ received by the hair cell through ion channels, causes depolarization, opens Ca channels to release NT to the synapse for the facial or glossopharyngeal nerve to receive stimulation

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12
Q

How does sweet/umami reception work?

A

sugar or glutamate binds to receptor, activating g-proteins/2nd messngr to release Ca++ and close K+ channels

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13
Q

How does bitter reception work?

A

Quanine binds, activating G-protein/2nd messngr to release Ca++ from endoplasmic reticulum; VERY sensitive to [LOW] as a protective response

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14
Q

What are g-proteins called in the gustation system?

A

gustducins

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15
Q

Which 2nd messngr is activated in sugar reception?

A

adenylate cyclase, producing cAMP

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16
Q

What other 2nd mssngr molecules can be active in gustation?

A

IP3 (inositol triphosphate) and DAG (diacylglycerol)

17
Q

Where are olfactory receptors located?

A

in the olfactory epithelium of the nasal cavity

18
Q

Sustentacular cells

A

olfactory cells that oxidize hydrophobic volatile odors

19
Q

What do basal stem cells do in olfaction?

A

They replace receptors damaged by the environment

20
Q

Anatomy of olfactory receptors

A

bipolar neurons with ciliated dendrites projecting into the nasal cavity

21
Q

What structure binds to odors?

A

proteins on the cilia of bipolar neurons

22
Q

How many different olfactory receptors do humans have?

A

~380

23
Q

1 odorant molecule stimulates ___ protein(s)

A

1

24
Q

How does smell reception work?

A

G-protein system stimulates activation of adenylate cyclase; produces cAMP to open Na and Ca channels; produces graded depolarization to produce AP

25
Q

How many G-proteins may be associated with 1 receptor protein in olfaction? What does this cause?

A

up to 50 = great sensitivity via amplification

26
Q

Are olfactory neurons myelinated?

A

No

27
Q

Where do olfactory neurons synapse?

A

on a specific type of glomerulus/group of glomeruli (by smell type, depending on complexity) in the olfactory bulb

28
Q

Odor identification is improved by _______

A

lateral inhibition

29
Q

What structures of the glomeruli synapse onto the olfactory cortex of the frontal and parietal lobes?

A

mitral and tufted neurons

30
Q

The piriform cortex is part of the _____ system

A

olfactory

31
Q

Where does smell stimulation travel after it reaches the piriform cortex?

A

hippocampus, amygdala, limbic system (bypasses the thalamus)

32
Q

Where does taste connect with smell?

A

at the prefrontal cortex