Lecture13: Pain Control Mechanisms Flashcards
1
Q
What are the 2 ways of inhibition via SupraSpinal Analgesia?
A
Presynaptic inhibition of neurotransmitter release and and direct postsynaptic inhibition of projection cells
2
Q
How does Pre synaptic inhibition function?
A
G proteins close calcium channels to prevent neurotransmitter release
3
Q
How does direct postsynaptic inhibition of projection cells act?
A
G proteins open k+ channels causing hyper-polarization
4
Q
What is gate control theory?
A
That non painful input closes the gates to painful input
5
Q
What is proof of gate control theory?
A
Counter-Stimulation analgesia
6
Q
Which inhibitory interneuron is activated in Counter-Stimulation analgesia?
A
Lamina 2
