Lecture24: Pathology Of Thyroid Gland

Question 1

2 causes of Hypothyroidism?

Answer 1

Radiation or Hasimoto’s thyroiditis

Question 2

Most common cause of Hypothyroidism?

Answer 2

Hashimoto’s Thyroiditis

Question 3

Explain Hasimoto’s thyroiditis?

Answer 3

A gradual thyroid failure secondary to autoimmune destruction of the gland

Question 4

Age range of Hashimoto’s thyroiditis and gender?

Answer 4

45-65 mainly female

Question 5

Which cells are destructive of the thyroid in Hashimoto’s thyroiditis?

Answer 5

CD-4 and CD-8 cells

Question 6

What is the state of the thyroid in Hasimoto’s thyroiditis?

Answer 6

Enlarged but painless

Question 7

What precedes Hashimoto’s Thyroiditis?

Answer 7

Transient Hashimotoxicosis

Question 8

Lab findings of Hashimoto’s thyroiditis?

Answer 8

Severely decreased T4 and T3, with elevated TSH levels

Question 9

Causes of Hyperthyroidism?

Answer 9

Graves and Thyroid adenoma

Question 10

What is the immunological explanation of Graves?

Answer 10

IgG prevents TSH from exerting its negative feedback effects

Question 11

What is the most common manifestation of thyroid disease?

Answer 11

GOITER

Question 12

What is GOITER?

Answer 12

A simple enlargement of the thyroid

Question 13

What causes goiter?

Answer 13

Dietary iodine deficiency