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Abdo Pathology > Lesson 3.2 - Panc Path Neoplasms > Flashcards

Lesson 3.2 - Panc Path Neoplasms Flashcards

1
Q

neoplasms of panc (4)

A
  • periampullary
  • cystic
  • pseudopapillary
  • endocrine, lipoma, mets
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2
Q

jaundice is the most important presentation for what type of neoplasm?

A

periampullary

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3
Q

how are periampullary neoplasms managed

A

Whipples Procedure (pancreaticoduodenectomy)

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4
Q

periampullary neoplasms include subcategories (4)

A
  • ductal adenocarcinoma
  • ampullary carcinoma
  • duodenal carcinoma
  • distal cholangiocarcinoma
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5
Q

most common primary pancreatic neoplasm

A

pancreatic ductal adenocarcinoma

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6
Q

ductal adenocarcinoma RF (8)

A 
male 
older age
smoking, obesity, diabetes
chronic pancreatitis
cirrhosis
fam history
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7
Q

classic S/S ductal adenocarcinoma (3)

A

jaundice
pain
weight loss

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8
Q

urine dark, stools pale

A

ductal adenocarcinoma sign

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9
Q

where do most periampullar adenocarcinomas originate in the panc

A

the head

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10
Q

double duct sign associated with

A

ductal periampullar adenocarcinoma

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11
Q

what can ductal periampullar adenocarcinoma lead to

A

if cancer originates in the head, can lead to Courvoisier GB

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12
Q

what is Courvoisier GB

A

obstruction to CBD causing enlarged GB and jaundice

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13
Q

what is the first thing we consider with treating periampullar cancer

A

if it can be resected (if over 2 cm or extension/vascular invasion, lymphadenopathy, then no resection)

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14
Q

what is whipples procedure

A

removal of head, uncinate, GB, CBD,
distal stomach, duodenum, part of jejunem,

anastomosis of CHD, remaining panc, stomach –> jejunem is the result

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15
Q

t/f cystic neoplasms can be benign or malignant

A

true

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16
Q

the majority of cystic neoplasms are

A

pseudocysts

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17
Q

ominous signs of cystic panc lesions (5)

A 
symptomatic pts
growth
diameter >3cm
internal soft tissue
mural/septal thickening
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18
Q

diseases assoc with cysts

A

polycystic kidney disease

von hippel-lindau disease

19
Q

what might suggest von hippel-lindau

A

multiple simple cysts

20
Q

what is von-hippel lindau

A

connective tissue disorder

21
Q

most common cystic neoplasms in order of prevalence

A
  • serous cystic
  • intraductal papillary muchinous
  • mucinous cystic
  • solid pseudopapillary
22
Q

t/f cystic neoplasms are usually benign or low grade malignancies

A

true

unless muchinous tumours - malignant

23
Q

microcystic adenoma is the same as

A

serous cystic neoplasm

24
Q

common location of serous cystic neoplasm

A

panc head

25
Q

serous cystic neoplasm sono app

A

myriad of tiny cysts too small for US

echogenic + posterior enhancement

26
Q

what neoplasm often presents as acute pancreatitis?

A

Intraductal papillary muchinous neoplasm

27
Q

where does Intraductal papillary muchinous neoplasm arise?

A

panc ducts

28
Q

hallmark sono app of intraductal papillary muchinous neoplasm

A

prominent ductal dilation

29
Q

what has the same appearance as sludge on US

A

mucin from IPMN

30
Q

what neoplasm is rare in men/more commonly in perimenopausal women

A

mucinous cystic neoplasm

31
Q

what neoplasm commonly occurs in panc body/tail

A

mucinous cystic neoplasm

32
Q

muchinous cystic neoplasm sono app (4)

A

unilocular/multilocular
thick/thin wall
septations
internal debris

33
Q

what tumour seen in young females

A

solid-pseudopapillary tumour

34
Q

what neoplasm commonly occurs in panc tail

A

solid-pseudopapillary tumour

35
Q

sono app pseudopapillary tumours (4)

A
  • round encapsulated masses
  • cystic, necrotic, soft tissue foci within
  • posterior enhancement
  • anechonic/hypo
36
Q

other panc masses

A

endocrine tumours
metastases
lipoma

37
Q

majority of panc endocrine tumours are what type of lesions

A

hyper-functioning

38
Q

when are non-hyperfunctioning lesions of panc endo tumours found

A

when they are larger and cause pain

39
Q

what is the most common pancreatic neoplasm

A

metastatic tumour

40
Q

primary sources of mets

A 
renal cell carcinoma*
breast*
lung*
colon
melanoma
stomach
41
Q

T/F US is unreliable in diagnosing fatty replacement

A

true, variable echogenicity

42
Q

what can fatty sparing cause

A

psuedomass in the uncinate process

43
Q

RF for severe fatty replacement (5)

A

cystic fibrosis, diabetes, obesity, NASH, old age

Abdo Pathology (24 decks)

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