Lipids 1 Flashcards Preview

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Flashcards in Lipids 1 Deck (24):
1

Name the 4 lipid classes

- Phospholipids
- TAG's
- Steroids
- Glycolipids

2

What causes unsaturation of FA's?

- C=C bonds cause a kink in the chain
- More bent
- More liquid

3

How many carbons long can humans no longer produced C=C bonds

Carbon 9

4

Name 2 essential FA's

- Lineloic Acid
- Linelonic acid

5

What does linelonic acid produce?

Omega 3 FA's

6

What is the role of omega 3 FA's

Lowering LDL cholesterol

7

What are bile salts?

- Emulsifiers
- Allow enzymes to break down digested FA's

8

What do lipids exist as in the blood?

Lipoproteins

9

Where does chylomicron transport FA's to and from?

- Small intestine to
- Adipose tissue

10

VLDL?

Liver to tissue

11

LDL

Tissue to blood vessels

12

HDL

Tissue to liver

13

How are TAG's digested?

- Degraded to monoacylglycerol and 2 FA's
- Absorbed through mucous cells in small intestine

14

What is steatorrhea and who is most susceptible?

- Fatty faeces
- Cystic fibrosis sufferers

15

Removal of what organ will reduce FA digestion?

Gall bladder as it produces bile

16

How are TAG stores used in response to hunger?

- Epinephrine released
- HSL phosphorylated
- HSL then releases FA's from TAG

17

What does HSL stand for?

Hormone Sensitive Lipase

18

How is HSL inhibited

High [blood glucose]

19

How are dietary lipids transported following digestion?

- Packaged into chylomicron
- Transported to adipose tissue to be resynthesised into TAG

OR

- Transported in and released into the lymph

20

What are chylomicron made of?

apoB-48

21

What is contained in chylomicron?

Lipoprotein lipase

22

What does lipoprotein lipase do in the chylomicron?

- Degrades TAG to glycerol and FA

23

How are phospholipids digested?

Broken down into lysophospholipid and FA

24

What are the uses of glycerol?

- Used in the liver to produce glycerol-3-phosphate which cane be used in glycolysis