lipids-1 Flashcards

1
Q

what are the three steps to naming lipids

A

1- how many carbons
2- how many double bonds
3- where the double bonds are

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2
Q

what are fatty acids (3 words)

A

amphipathic carboxylic acid

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3
Q

what are 2 things that fatty acids are a key component of

A

storage and membrane lipids

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4
Q

are fatty acids more commonly cis or trans

A

cis

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5
Q

how does degree of saturation relate to melting point

A

higher degree of saturation=higher melting point

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6
Q

what does a low degree of saturation mean to melting point

A

low melting point

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7
Q

what does a high degree of saturation mean to melting point

A

high melting point

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8
Q

why are membrane lipids amphipathic (what makes it so)

A

hydrophilic end / polar head group

hydrophobic end / fatty acid tail

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9
Q

what charge or membrane lipids in the polar part of the lipid

A

neutral or negative

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10
Q

what do variations in membrane lipid composition affect

A

the specific nature of the membrane

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11
Q

what are the 5 primary types of membrane lipids

A
  • glycerophospholipids
  • sphingolipids
  • galactolipids
  • tetraether lipids
  • sterol lipids
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12
Q

what are the 4 classes of lipids

A
  • phospholipids
  • glycolipids
  • sulfolipids
  • ether lipids
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13
Q

what are 2 types of phospholipids

A

glycerophospholipids and sphingolipids

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14
Q

what is a type of phospholipid sphingolipid

A

sphingomyelin

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15
Q

what are 3 types of glycolipids

A

sphingolipid
inositol lipids
galactolipids

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16
Q

what are 3 types of phospholipid sphingolipid

A

cerebrosides
globosides
gangliosides

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17
Q

what are ether lipids / another name for it

A

tetraether

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18
Q

what is the central core of glycerophospholipids

A

glycerol-3-phosphate

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19
Q

is glycerol chiral

A

no

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20
Q

is glycerol-3-phosphate chiral

A

yes

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21
Q

what is the chiral center of glycerol-3-phosphate

A

C2

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22
Q

is R1 or R2 in glycerophospholipids more likely to be saturated

A

R1

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23
Q

is R1 or R2 in glycerophospholipids more likely to be unsaturated

24
Q

how are fatty acids connected to the glycerol backbone

A

ester linkages (carbon 1 and 2)

25
is the fatty acid attached to C2 of glycerol usually saturated or unsaturated
unsaturated
26
is the fatty acid attached to C1 of glycerol usually saturated or unsaturated
saturated
27
what kind of substituent is often attached to the phosphate of glycerophospholipids
a polar substituent
28
what kind of bond would it be if an alcohol was attached to the phosphate of a glycerophospholipid
phosphodiester
29
what ultimately determines the "type" of glycerophospholipid
the substituent that is attached to the phosphate
30
what is phosphatidic acid
a glycerophospholipid with no additional polar group (so just an H)
31
what is the charge of phosphatidic acid
-1 (charge just from glycerol-3-phosphate)
32
what is the charge of phosphatidate
-2 (charge from glycerol-3-phosphate and the PO4-)
33
what contributes the normal -1 charge on glycerophospholipids
the phosphate from glycerol-3-phosphate
34
what kind of charges can the head groups of glycerophospholipids contribute and what does this do to the charge of the whole lipid
positive or negative (or neutral) | making the whole lipid neutral or negative
35
do the lipid groups attached to C1 and C2 vary depending on the glycerophospholipid head group
yes
36
what is phosphatidate
the conjugate base of phosphatidic acid
37
what is the charge of ethanolamine as part of lipid
0
38
what is the charge of choline as part of lipid
0
39
what is the charge of serine as part of lipid
-1
40
what is the thing attached to phosphate in phosphatidic acid
H
41
what is the thing attached to phosphate in choline
CH2CH2N(CH3)3+
42
what is the thing attached to phosphate in ethanolamine
CH2CH2NH3+
43
what is the thing attached to phosphate in ethanolamine
CH2CH2NH3+
44
what is the thing attached to phosphate in serine
CH2CH(CH3+)COO-
45
what is the charge of myo-inositol as part of lipid
-1
46
what is the charge of glycerol as part of lipid
-1
47
what is the charge of phosphatidyl glycerol as part of lipid (as the X group)
-2
48
what kind of lipid is phosphatidylinositol
glycolipid
49
what do you call it when H is the R group in the phosphate head of a glycerophospholipid
phosphatidic acid
50
what do you call it when ethanolamine is the R group in the phosphate head of a glycerophospholipid
phosphatidylethanolamine
51
what do you call it when choline is the R group in the phosphate head of a glycerophospholipid
phosphatidylcholine
52
what do you call it when serine is the R group in the phosphate head of a glycerophospholipid
phosphatidylserine
53
what do you call it when myo-inositol is the R group in the phosphate head of a glycerophospholipid
phosphatidylinositol
54
what do you call it when glycerol is the R group in the phosphate head of a glycerophospholipid
phosphatidylglycerol
55
what do you call it when phosphatidylglycerol is the R group in the phosphate head of a glycerophospholipid
diphosphatidylglycerol