Lipids/Cell Membrane Flashcards Preview

Question 1

1

Property of lipids

Answer

Heterogeneous group of compounds, share: 1. Insolubility in water based solutions. 2. Solubility in organic/non-polar solvent.s

Question 2

2

Normal saturated fatty acids are generally more soluble in __?

Answer

Chloroform

Question 3

3

SA FA are generally less soluble in __ ?

Answer

Acetonitrile

Question 4

4

5 Biological Functions of Lipids?

Answer

Storage of Energy Membrane Structure Signalling Molecules Cofactors for enzymes Antioxidants

Question 5

5

Branch 1 Classification of Lipid

Answer

Complex and Biologically Active Lipids

Question 6

6

Difference between Complex and Biologically Active Lipids

Answer

Complex = FA Biologically active = NO FA

Question 7

7

Branches of complex lipids (FA)?

Answer

Storage and Structural Lipids

Question 8

8

Difference between storage and structural lipids?

Answer

Storage = non-polar Structural = polar

Question 9

9

examples of storage (non-polar) lipids

Answer

Triglycerides Waxes

Question 10

10

examples of structural (polar) lipids

Answer

Phospholipids Sphingolipids

Question 11

11

Examples of biologically active lipids (No FA)

Answer

Prostaglandins Steroids

Question 12

12

Define fatty acid

Answer

Amphipathic molecules with hydrocarbon chains containing 3 to 35 carbons plus carboxylic group.

Question 13

13

pKa of COOH groups?

Answer

<5 ... therefore will be fully ionized after this time.

Question 14

14

Almost all natural FA have ____

Answer

an even # of carbons

Question 15

15

FA can be ___

Answer

saturated or unsaturated

Question 16

16

What are FA physical properties based on?

Answer

1) Length of hydrocarbon chain 2) Degree of saturation

Question 17

17

All naturally occurring double bonds have __

Answer

CIS configuration

Question 18

18

Most common FA length?

Answer

C14 to C18

Question 19

19

What is interesting about the 4 carbon FA, or butanoic acid?

Answer

-infinitely water soluble -solubility decreases w/ increased hydrocarbon chain length.

Question 20

20

Solubility of Lauric acid? (12 carbon FA?)

Answer

partially soluble to the extent of 0.06g per gram of water

Question 21

21

Fatty acids with C10 or greater form ___ at room temp

Answer

Waxy solids

Question 22

22

Fatty acids with C9 or lower saturates or unsaturated HC chains form ___ at room temperature?

Answer

Oily solids

Question 23

23

What does the prefix "alpha" indicate?

Answer

Normal or unbranched structure. i.e alpha-linolenic acid.

Question 24

24

Double bonds in FA chains produce what?

Answer

kinks and bends

Question 25

25

Due to kinks and bends in unsaturated FA ... this causes what?

Answer

1) Unsaturated FA are LESS packed VS saturated 2) LESS ordered packing = WEAKER intermolecular interactions (vanderwall forces) 3) LOWER melting points for unsaturated fatty acids.

Question 26

26

Which fatty acids can humans not synthesize? Why do we need them?

Answer

LinoLEIC acid, Omega 6. LinoLENIC acid, Omega 3. Need them to synthesize other needed FA, such as AA, DHA, EPA and n-3 and n-6 eicosanoids.

Question 27

27

Importance of omega 3?

Answer

-inhibit formation of thromboxane A2 (eicosanoids) -> associated with platelet aggregation + clot formation.

Question 28

28

Omega 3 FA are associated with decrease risk of what disease?

Answer

Coronary diseases

Question 29

29

3 major typed of omega 3 fatty acids?

Answer

-alpha linolenic cid (ALA) -EPA -DHA

Question 30

30

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