Liver

Question 1

Reticulin stain

Answer 1

Silver stain. Highlights the reticular network surrounding (deliminating) liver sinusoids

Question 2

Acute fulminant liver failure

Answer 2

Occurs within 26 weeks from initial liver injury

With or without preexisting liver disease

Question 3

Acute fulminant liver failure caused by

Answer 3

Massive hepatic necrosis

Question 4

Hepatic encephalopathy can be caused by

Answer 4

Acute liver failure

Question 5

Cirrhosis is associated with what type of liver failure

Answer 5

Chronic

Question 6

Cirrhosis liver staining

Answer 6

Connective tissue stain- Masson’s trichrome- highlights COLLAGEN

Question 7

Assessment of coagulability due to liver disease is done by

Answer 7

Prothrombin time

Question 8

Acute hepatitis- bridging necrosis

Answer 8

A confluence necrosis connecting the portal tract to terminal venues. Best seen with reticulin stain.

Question 9

Chronic hepatitis defining histological character

Answer 9

Mononuclear PORTAL infiltration

Question 10

Interface hepatitis

Answer 10

A chronic hepatitis histological pattern, includes:

1. inflammatory lymphocytes infiltration
2. hepatocyes necrosis (immediately surrounding portal tracts)

Question 11

hepatitis B ground glass appearance (histo)

Answer 11

Due to CYTOPLASMIC depositions of HBsAg

Question 12

Feathery degeneration of hepatocytes

Answer 12

Droplets of bile pigments accumulate within hepatocytes, take on a fine foamy appearance.

• cholestasis
• obstruction of extrahepatic bile ducts

Question 13

Ascending cholangitis

Answer 13

Indicated a BACTERIAL infection of the INTRAhepatic bile ducts!!!