Liver tumours and lesions Flashcards Preview

Gastrointestinal (LECTURE NOTES) > Liver tumours and lesions > Flashcards

Flashcards in Liver tumours and lesions Deck (12):
1

What does classification around liver lesions revolve around

Whether the lesion is likely to be benign or malignant q

2

The majority of liver lesions are symptomatic. True or False.

False - most are asymptomatic

3

Raised levels of what are indicative of Hepatocellular carcinoma

Raised levels of Alpha-fetoprotein

4

What is the initial radiological investigation

Ultrasound

5

Why might a liver biopsy be required

To determine the diagnosis (presence or absence of malignancy)
Presence or absence of underlying liver disease and cirrhosis

6

Why would biopsy be avoided and why

If HCC or hydatid (cyst) is strongly suspected - to avoid the risk of seeding the tumour along the biopsy tract

7

What is the treatment for benign liver lesions

Most don't need any treatment
Only some that are large close to the capsule of the liver and causing pain or when central lesions cause biliary obstruction.

8

What is the treatment for malignant liver lesions

Depends on the condition and the underlying liver disease

9

What types of primary cancer which have metastasised to the liver are potentially curable

Colorectal adenocarcinoma and neuroendocrine tumours

10

What might neoadjuvant systemic chemotherapy do

Increase the proportion of patients with resectable disease

11

What does treatment of HCC localised to the liver depend on

The presence or absence of cirrhosis

12

When is liver transplantation indicated in hepatocellular carcinoma

When the lesion is small, extrahepatic disease is non-existent and hepatic reserve is poor