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Flashcards in Liver tumours and lesions Deck (12)
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What does classification around liver lesions revolve around

Whether the lesion is likely to be benign or malignant q


The majority of liver lesions are symptomatic. True or False.

False - most are asymptomatic


Raised levels of what are indicative of Hepatocellular carcinoma

Raised levels of Alpha-fetoprotein


What is the initial radiological investigation



Why might a liver biopsy be required

To determine the diagnosis (presence or absence of malignancy)
Presence or absence of underlying liver disease and cirrhosis


Why would biopsy be avoided and why

If HCC or hydatid (cyst) is strongly suspected - to avoid the risk of seeding the tumour along the biopsy tract


What is the treatment for benign liver lesions

Most don't need any treatment
Only some that are large close to the capsule of the liver and causing pain or when central lesions cause biliary obstruction.


What is the treatment for malignant liver lesions

Depends on the condition and the underlying liver disease


What types of primary cancer which have metastasised to the liver are potentially curable

Colorectal adenocarcinoma and neuroendocrine tumours


What might neoadjuvant systemic chemotherapy do

Increase the proportion of patients with resectable disease


What does treatment of HCC localised to the liver depend on

The presence or absence of cirrhosis


When is liver transplantation indicated in hepatocellular carcinoma

When the lesion is small, extrahepatic disease is non-existent and hepatic reserve is poor