Lorazepam (Ativan) Flashcards Preview

Paramedic Drugs Set 7 - Sedatives / Paralytics > Lorazepam (Ativan) > Flashcards

Flashcards in Lorazepam (Ativan) Deck (7)
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1

Classification

Benzodiazepine, anxiolytic, sedative

2

Mechanism of Action

  • Interacts with GABA-benzodiazepine, receptor complexes, (benzodiazepine agonist)
  • Antianxiety effects
  • Sedation
  • Reducton of seizure activity

3

Indications

  • Status epilepticus
  • Relief of severe anxiety
  • Sedation prior to cardioversion or pacing

4

Contraindications

  • Hypersensitivity
  • Altered LOC of unknown etiology
  • Acute narrow angle glaucoma
  • Patients with sleep apnea syndrome

5

Adverse Effects

  • Hypotension, bradycardia
  • Dizziness, ataxia, fatigue, drowsiness, amnesia
  • Respiratory depression, apnea

6

Administration

  • Seizures: 4 mg slow IV (2 mg/min) for patients 18+
  • Sedation: 2 mg total (or 0.04 mg/kg) whichever is smaller.
  • Anxiety: 2 mg total (or 0.04 mg/kg) whichever is smaller.

7

Special Considerations

  • Immedietely prior to IV use ativan must be diluted with equal volume of compatible solution. Contents should be mixed thoroughly by gently inverting the container repeatedly until a homogenous solution results. Do not shake vigorously as this will result in air entrapment. When properly diluted the drug may be injected directly into vein or into tubing of an existing IV infusion. The rate of injection should not exceed 2 mg/min.