Succinylcholine (Ancetine) Flashcards Preview

Paramedic Drugs Set 7 - Sedatives / Paralytics > Succinylcholine (Ancetine) > Flashcards

Flashcards in Succinylcholine (Ancetine) Deck (7)
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1

Classification

Neuromuscular blocker, depolarizing

2

Mechanism of Action

  • Competes with acetylcholine receptor of the motor end plate on the muscle cell, resulting in muscle paralysis

3

Indications

  • To induce neuromuscular blockade to facilitate intubation

4

Contraindications

  • Malignant hyperthermia,
  • Severe burns
  • Severe truma

5

Adverse Effects

  • Anaphylactoid reactions
  • Respiratory depression, apnea, bronchospasm
  • Cardiac arrythmias, malignant hyperthermia
  • Hyper/hypotension
  • Muscle fasciculation

6

Administration

  • Adult: 0.5 mg/kg IV/IO or 3-4 mg/kg IM (max 150 mg)

7

Special Considerations

  • IV results in neuromuscular blockade in 30-60 seconds, IM in 2-3 minutes
  • IV in infants and children can potentially result in profound bradycardia, and, occasionally, asystyole. Bradycardia can be reduced by pretreating with atropine.
  • Has significantly prolonged effect with nerve gas agents or organophosphate poisoning.