Lymphatic System Flashcards
(37 cards)
Where is the spleen located
In the left hypochondrium
Function of spleen
Filter BLOOD not lymph fluid
Removes old RBC
What supplies the spleen
Splenic artery from the Coeliac trunk
What structures are related to the spleen
Stomach
Lung
Diaphragm
Ribs 9-11
Splenic flexure
Pancreas tail
Kidney
What happens to the spleen if there is portal hypertension
Spleen may become enlarged due to back flow from hepatic portal vein back into superior mesenteric vein and into splenic vein
What is the primary site of B cell maturation after leaving the bone marrow
Spleen
What is the difference between yellow and red marrow
Red marrow is where erythrocytes are produced. Yellow marrow is when there is an accumulation of fat
Where can red marrow be found in adults
Found in epiphysis of long bones,
Short bones
Flat bones,
Irregular bones
What supplies the bone marrow
Nutrient arteries that pierce the diaphysis
What type of bone makes up almost all of the adult skeleton
Lamellar bone
What forms cancellous or woven bone
Hgih,y active osteoblasts in children or adults who are undergoing fracture repair
What happens to bone marrow as we age
Yellow marrow replaces red marrow
Where is the thymus locates
Anterior and superior to the heart
Extends between the thyroid gland (superiorly) and fourth costal cartilage (inferiorly) within the superior mediastinum and anterior part of inferior mediastinum.
How many lobes does the thymus have
2 connected by an isthmus
Function of the thymus
Maturation and education of T cells via positive and negative selection
What is the histological divisions of the thymus
Cortex and medulla
What 2 structures are the thymus related to
Thyroid gland and 4th costal cartilage
What supplies the thymus
Superior and inferior thyroid arteries
Internal thoracic arteries
What drains the thymus
Internal thoracic, thyroid veins -> left brachiocephallic -> superior vena cava
What is in the white pulp of the spleen
White bloood cells like T cells and B cells
Lymphoid nodules
Germinal centres
Hubs for T cells and B cells communication
What is found in the red pulp
Macrophages to destroy old rbc
Venous sinusoids
White pulp blood supply
Splenic artery -> trabeculae arteries -> central arteriole -> lymphoid nodules with germinal centres
Red pulp blood supply
Venous sinusoids