Lymphatic Tissue and Organs Flashcards

(41 cards)

1
Q

Primary lympathic tissue

A

site of development of maturation of lymphocytes into immuncompetent cells

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2
Q

Two kinds of primary lymphatic tissues

A

bone marrow

thymus

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3
Q

3 kinds of secondary lymphatic tissue

A

lymph nodes
MALT
Spleen

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4
Q

Function of secondary lymphatic tissues

A

confrontation with antigens of pathogens occurs here

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5
Q

Lymph Nodes

A

filter lymph

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6
Q

MALT

A

surveillance

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7
Q

Spleen

A

filters blood
largest lymphatic organ
site of B and T lymphocyte proliferation
perpetual graveyard for cells

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8
Q

GALT

A

gut associated lymphatic tissue

in lamina propria of GI tract

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9
Q

BALT

A

bronchus associated lymphathic tissue

located in lamina propria of respiratory tract

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10
Q

GU tract

A

found in lamina propria of gentiourinary tract

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11
Q

Lamina Propria

A

latin for first layer

loose CT just inside epithelium

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12
Q

What cell types are seen in diffuse lymphatic tissue

A

lymphocytes
monocytes
macrophages
plasma cells

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13
Q

Solitary Lymphatic Nodules

A

are temporary

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14
Q

Aggregates of Lymphatic Nodules

A

are permanent. ex) peyer’s patches, appendix, BALT

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15
Q

Tonsils

A

aggregates of Lymphatic Nodules with B-lymphocytes

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16
Q

How can you tell it’s a palatine tonsil

A
  • stratified, squamous, nonkeratinized epithelium
  • secondary lymphatic nodules
  • crypts
  • cap made of dense irregular collagenous CT
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17
Q

Regions of lymph nodes

A

cortex and medulla

18
Q

Convex surface of lymph vessel

A

where lymph vessels bring lymph to the lymph node

19
Q

Concave surface of lymph vessel

A

bottom surface

has hilum

20
Q

Sinuses

A

pathogens and toxins are filtered out here

21
Q

Lymph node parechyma

A

cellular part

22
Q

Where are B lymphocytes found

A

nodules/cortex

23
Q

Where are T lymphocytes found

24
Q

2 sources of lymphocytes

A

high endothelial venules in paracortex (main source)

afferent lymph vessels

25
Where do T lymphocytes mature
thymus. | but originate in bone marrow
26
Where are the most immature cells found
outer layer of cortex
27
Where are the most mature cells found
inner layer of cortex
28
Medulla
innermost layer where mature, immocompetent lymphocytes reach after tehy travel through the cortex
29
What does the thymus NOT have?
- afferent lymphatic vessels - 3D reticular fiber framework - lymphatic nodules - B-lymphocytes - sinuses or sinusoids
30
Type I Epithelioreticular cells
create an antigen proof compartment for the T-lymphocytes in the cortex
31
Blood Thymus barrier
isolates T-lymphocytes of the cortex from macromolecules circulating in the blood
32
What is the blood thymus barrier made of?
cortical capillary endothelium basal lamina macrophages type I epithelioreticular cells
33
Type VI epithelioreticular cells
form hassall's corpuscles in the medulla
34
Type II epithelioreticular cells
form a 3D reticulum with their cell processes to suspend T-lymphocytes in the cortex
35
Type III epithelioreticular cells
isolate cortex from medula
36
Type IV epithelioreticular cells
similar to type III | found at corticomedullary junction, isolating cortex from medulla
37
Type V epithelioreticular cells
similar to type II | form a 3D reticulum with their cell processes to suspend T-lymphocytes in the medulla
38
DiGeorge's Syndrome
developmental disorder cannot produce T lymphocytes death from infection
39
What is parenchyma of spleen divided into
red pulp (majority is this) and white pulp (smaller islands formed by lymphatic islands)
40
Red Pulp Cord (Cord of Billroth)
contains macrophages
41
Open circulation of spleen
arterial capillaries end near the sinusoids, and blood from these capillaries seeps into splenic cords and then into splenic sinus